The genomes of virtually all organisms contain repetitive sequences that are generated by
the activity of transposable elements (transposons). Transposons are mobile genetic …

Inflammasomes are protein complexes of the innate immune system that initiate
inflammation in response to either exogenous pathogens or endogenous danger signals …

HIV reverse transcriptase (RT) inhibitors are the important components of highly active
antiretroviral therapies (HAARTs) for anti-HIV treatment and pre-exposure prophylaxis in …

Preventing islet β‐cells death is crucial for treating type 2 diabetes mellitus (T2DM).
Currently, clinical drugs are being developed to improve the quality of T2DM care and self …

Our defenses against infection rely on the ability of the immune system to distinguish
invading pathogens from self. This task is exceptionally challenging, if not seemingly …

Type 2 diabetes and atherosclerosis have gradually garnered great attention as
inflammatory diseases. Previously, the fact that Interleukin-1β (IL-1β) accelerates the …

Inflammation plays a crucial role in cancer progression, but the relevance of the
inflammasome remains unclear. Alu RNA was the first endogenous nucleic acid shown to …

Detection of microbial products by multiprotein complexes known as inflammasomes is
pivotal to host defense against pathogens. Nucleotide-binding domain leucine-rich repeat …

Alu retroelements propagate via retrotransposition by hijacking long interspersed nuclear
element-1 (L1) reverse transcriptase (RT) and endonuclease activities. Reverse …

Although some cohort studies have indicated a close association between diabetes and
HCC, the underlying mechanism about the contribution of diabetes to HCC progression …