This review focuses on organometallic nucleosides. It discusses: a) the synthetic methods
that enable the site-specific incorporation of organometallic entities into the nucleoside …

Xeno nucleic acids (XNA) are an increasingly important class of hypermodified nucleic acids
with great potential in bioorganic chemistry and synthetic biology. Glycol nucleic acid (GNA) …

Threofuranosyl nucleic acid (TNA) is an analogue of DNA with a shift in the internucleotide
linkages from the wild-type 5'-to-3'direction to 3'-to-2.'This alteration leads to higher chemical …

A highly efficient Pd-catalyzed asymmetric formal [3+ 2] cycloaddition using α-N-heterocyclic
acrylates to react with vinyl epoxides has been achieved for the first time to access chiral …

To address the challenge of meta nitration of 6-arylpurine substrates, a versatile ruthenium
catalyzed meta C–H nitration is developed. The use of a sterically hindered phosphine …

Dihydropyrimidinase (DHPase) catalyzes the reversible cyclization of dihydrouracil to N-
carbamoyl-β-alanine in the second step of the pyrimidine degradation pathway. Whether 5 …

Aptamers are powerful recognition elements that can bind a large number of target
molecules, including metal ions, small molecules, proteins, enzymes, even complex targets …

A novel and efficient electrochemical method for electroselective and controlled cross-
coupling of isoindolinones with equivalent alcohols has been developed without the need …

The enantioselective synthesis and electrochemistry of the first ferrocenyl GNA nucleosides
is reported. These compounds were obtained by a Sharpless asymmetric dihydroxylation …

A series of phosphonated carbocyclic 2′‐oxa‐3′‐aza‐nucleosides were synthesized via
1, 3 dipolar cycloaddition and evaluated for their in vitro antiproliferative activity against the …