Collagen is the oldest and most abundant extracellular matrix protein that has found many
applications in food, cosmetic, pharmaceutical, and biomedical industries. First, an overview …

Collagen is a ubiquitous biomaterial in vertebrate animals. Although each of its 28 subtypes
contributes to the functions of many different tissues in the body, most studies on collagen or …

Uric acid is a damage-associated molecular pattern (DAMP), released from ischemic tissues
and dying cells which, when crystalized, is able to activate the NLRP3 inflammasome …

Regenerative therapies for bone and cartilage injuries are currently unable to replicate the
complex microenvironment of native tissue. There are many tissue engineering approaches …

Extracellular matrix (ECM) composition, organization, and compliance provide both
architectural and chemical cues that modulate tissue structure and function. ECM produced …

Tissue engineering technology has made major advances with respect to the repair of
injured tissues, for which scaffolds and cells are key factors. However, there are still some …

Under normal physiological conditions, tissue remodeling in response to injury leads to
tissue regeneration without permanent damage. However, if homeostasis between synthesis …

2007-09-24 Assigned to UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH
SYSTEM OF HIGHER EDUCATION reassignment UNIVERSITY OF PITTSBURGH-OF THE …

An open wound is highly susceptible to microbial infection leading to elevated level of
inflammatory response. For prompt healing, a wound requires a biomimetic dressing …

Objective To investigate the inhibitory effects of 38% silver diamine fluoride (SDF) on
demineralised dentine. Methods Human dentine blocks were demineralised and allocated …