Recognition in the domain of molecular chirality: from noncovalent interactions to separation of enantiomers
It is not a coincidence that both chirality and noncovalent interactions are ubiquitous in
nature and synthetic molecular systems. Noncovalent interactivity between chiral molecules …
nature and synthetic molecular systems. Noncovalent interactivity between chiral molecules …
Native and substituted cyclodextrins as chiral selectors for capillary electrophoresis enantioseparations: Structures, features, application, and molecular modeling
CDs are cyclic oligosaccharides consisting of α‐d‐glucopyranosyl units linked through 1, 4‐
linkages, which are obtained from enzymatic degradation of starch. The coexistence of …
linkages, which are obtained from enzymatic degradation of starch. The coexistence of …
Advances in the use of cyclodextrins as chiral selectors in capillary electrokinetic chromatography: fundamentals and applications
Q Zhu, GKE Scriba - Chromatographia, 2016 - Springer
Capillary electrokinetic chromatography is generally recognized as a versatile and robust
capillary electromigration technique for the separation of enantiomers. In this mode, one or …
capillary electromigration technique for the separation of enantiomers. In this mode, one or …
Cyclodextrin-assisted SERS determination of fluoroquinolone antibiotics in urine and blood plasma
This paper describes the use of cyclodextrins (CDs) to improve the determination of
fluoroquinolone antibiotics in human body fluids using surface-enhanced Raman …
fluoroquinolone antibiotics in human body fluids using surface-enhanced Raman …
Cyclodextrins in capillary electrophoresis: recent developments and new trends
L Escuder-Gilabert, Y Martín-Biosca… - … of Chromatography A, 2014 - Elsevier
Despite the fact that extensive research in the field of separations by capillary
electrophoresis (CE) has been carried out and many reviews have been published in the …
electrophoresis (CE) has been carried out and many reviews have been published in the …
[HTML][HTML] Enantioseparation of ofloxacin using a liquid–liquid extraction system based on hydrophobic eutectic solvents
The enantioseparation of chiral drugs is a major challenge for the pharmaceutical industry
as the pharmacological activities of the enantiomers may differ, which can lead to severe …
as the pharmacological activities of the enantiomers may differ, which can lead to severe …
Characterization of thymoquinone/hydroxypropyl-β-cyclodextrin inclusion complex: Application to anti-allergy properties
Thymoquinone is an effective phytochemical compound in the treatment of various diseases.
However, its practical administration has been limited due to poor aqueous solubility and …
However, its practical administration has been limited due to poor aqueous solubility and …
Characteristic of Cyclodextrins: Their role and use in the pharmaceutical technology
M Lachowicz, A Stańczak… - Current Drug Targets, 2020 - ingentaconnect.com
About 40% of newly-discovered entities are poorly soluble in water, and this may be an
obstacle in the creation of new drugs. To address this problem, the present review article …
obstacle in the creation of new drugs. To address this problem, the present review article …
Thermodynamics and molecular insight in guest–host complexes of fluoroquinolones with β-cyclodextrin derivatives, as revealed by ATR-FTIR spectroscopy and …
IM Le-Deygen, AA Skuredina, IV Uporov… - Analytical and …, 2017 - Springer
Abstract β-Сyclodextrin (CD) is a perspective class of excipients used in pharmaceutical
formulations to enhance solubility, bioavailability, and pharmacokinetics of various poorly …
formulations to enhance solubility, bioavailability, and pharmacokinetics of various poorly …
Applications of nuclear magnetic resonance spectroscopy for the understanding of enantiomer separation mechanisms in capillary electrophoresis
A Salgado, B Chankvetadze - Journal of Chromatography A, 2016 - Elsevier
This review deals with the applications of nuclear magnetic resonance (NMR) spectroscopy
to understand the mechanisms of chiral separation in capillary electrophoresis (CE). It is …
to understand the mechanisms of chiral separation in capillary electrophoresis (CE). It is …