Biospectroscopy to metabolically profile biomolecular structure: a multistage approach linking computational analysis with biomarkers

JG Kelly, J Trevisan, AD Scott… - Journal of proteome …, 2011 - ACS Publications
Biospectroscopy is employed to derive absorbance spectra representative of biomolecules
present in biological samples. The mid-infrared region (λ= 2.5 μm− 25 μm) is absorbed to …

Using Fourier transform IR spectroscopy to analyze biological materials

MJ Baker, J Trevisan, P Bassan, R Bhargava… - Nature protocols, 2014 - nature.com
IR spectroscopy is an excellent method for biological analyses. It enables the
nonperturbative, label-free extraction of biochemical information and images toward …

Vibrational spectroscopic methods for cytology and cellular research

G Clemens, JR Hands, KM Dorling, MJ Baker - Analyst, 2014 - pubs.rsc.org
The use of vibrational spectroscopy, FTIR and Raman, for cytology and cellular research has
the potential to revolutionise the approach to cellular analysis. Vibrational spectroscopy is …

Occupational exposure to polycyclic aromatic hydrocarbons and elevated cancer incidence in firefighters

AA Stec, KE Dickens, M Salden, FE Hewitt, DP Watts… - Scientific reports, 2018 - nature.com
Cancer incidence appears to be higher amongst firefighters compared to the general
population. Given that many cancers have an environmental component, their occupational …

Distinguishing cell types or populations based on the computational analysis of their infrared spectra

FL Martin, JG Kelly, V Llabjani, PL Martin-Hirsch… - Nature protocols, 2010 - nature.com
Infrared (IR) spectroscopy of intact cells results in a fingerprint of their biochemistry in the
form of an IR spectrum; this has given rise to the new field of biospectroscopy. This protocol …

Standardization of complex biologically derived spectrochemical datasets

CLM Morais, M Paraskevaidi, L Cui, NJ Fullwood… - Nature protocols, 2019 - nature.com
Spectroscopic techniques such as Fourier-transform infrared (FTIR) spectroscopy are used
to study interactions of light with biological materials. This interaction forms the basis of …

Low-dose carbon-based nanoparticle-induced effects in A549 lung cells determined by biospectroscopy are associated with increases in genomic methylation

J Li, M Tian, L Cui, J Dwyer, NJ Fullwood, H Shen… - Scientific reports, 2016 - nature.com
Nanotechnology has introduced many manufactured carbon-based nanoparticles (CNPs)
into our environment, generating a debate into their risks and benefits. Numerous …

Interactions of multiwalled carbon nanotubes with algal cells: Quantification of association, visualization of uptake, and measurement of alterations in the composition …

S Rhiem, MJ Riding, W Baumgartner, FL Martin… - Environmental …, 2015 - Elsevier
Carbon nanotubes (CNTs) are considered promising materials in nanotechnology. We
quantified CNT accumulation by the alga Desmodesmus subspicatus. Cells were exposed …

Concentration-dependent effects of carbon nanoparticles in gram-negative bacteria determined by infrared spectroscopy with multivariate analysis

MJ Riding, FL Martin, J Trevisan, V Llabjani… - Environmental …, 2012 - Elsevier
With increasing production of carbon nanoparticles (CNPs), environmental release of these
entities becomes an ever-greater inevitability. However, many questions remain regarding …