Rational design of biomaterials to potentiate cancer thermal therapy

Y Zhu, Q Li, C Wang, Y Hao, N Yang, M Chen… - Chemical …, 2023 - ACS Publications
Cancer thermal therapy, also known as hyperthermia therapy, has long been exploited to
eradicate mass lesions that are now defined as cancer. With the development of …

Recent advances on endogenous/exogenous stimuli-triggered nanoplatforms for enhanced chemodynamic therapy

Q Sun, Z Wang, B Liu, F He, S Gai, P Yang… - Coordination Chemistry …, 2022 - Elsevier
In view of certain unique internalization features of the tumor microenvironment
(TME)(mainly including hypoxia, acidity and higher concentrations of H 2 O 2 and GSH) …

Polarization of Tumor-Associated Macrophages by Nanoparticle-Loaded Escherichia coli Combined with Immunogenic Cell Death for Cancer Immunotherapy

B Wei, J Pan, R Yuan, B Shao, Y Wang, X Guo… - Nano Letters, 2021 - ACS Publications
The tumor immunosuppressive microenvironment greatly limits the efficacy of
immunotherapy. Tumor-associated macrophages (TAMs) are the most abundant …

Spatiotemporal control of engineered bacteria to express interferon-γ by focused ultrasound for tumor immunotherapy

Y Chen, M Du, Z Yuan, Z Chen, F Yan - Nature Communications, 2022 - nature.com
Bacteria-based tumor therapy has recently attracted wide attentions due to its unique
capability in targeting tumors and preferentially colonizing the core area of the tumor …

Surface-modified bacteria: synthesis, functionalization and biomedical applications

S Lin, F Wu, Y Zhang, H Chen, H Guo… - Chemical Society …, 2023 - pubs.rsc.org
The past decade has witnessed a great leap forward in bacteria-based living agents,
including imageable probes, diagnostic reagents, and therapeutics, by virtue of their unique …

Smart and bioinspired systems for overcoming biological barriers and enhancing disease theranostics

X Li, Y Gao, H Li, JP Majoral, X Shi, A Pich - Progress in Materials Science, 2023 - Elsevier
Nanomedicine has emerged as a promising mean to improve theranostic efficacy and
reduce side effects. Currently, only very small percentage of injected dose reaches the solid …

Decorated bacteria and the application in drug delivery

F Wu, J Liu - Advanced Drug Delivery Reviews, 2022 - Elsevier
The use of living bacteria either as therapeutic agents or drug carriers has shown great
potential in treating a multitude of intractable diseases. However, cells are often fragile to …

Cell membrane-coated mimics: a methodological approach for fabrication, characterization for therapeutic applications, and challenges for clinical translation

V Chugh, K Vijaya Krishna, A Pandit - ACS nano, 2021 - ACS Publications
Cell membrane-coated (CMC) mimics are micro/nanosystems that combine an isolated cell
membrane and a template of choice to mimic the functions of a cell. The design exploits its …

[HTML][HTML] Recent strategies for nano-based PTT combined with immunotherapy: from a biomaterial point of view

X Huang, Y Lu, M Guo, S Du, N Han - Theranostics, 2021 - ncbi.nlm.nih.gov
Cancer has been a great threat to humans for decades. Due to the limitations of
monotherapy, combinational therapies such as photothermal therapy (PTT) and …

Prebiotics‐encapsulated probiotic spores regulate gut microbiota and suppress colon cancer

DW Zheng, RQ Li, JX An, TQ **e, ZY Han… - Advanced …, 2020 - Wiley Online Library
While microbial‐based therapy has been considered as an effective strategy for treating
diseases such as colon cancer, its safety remains the biggest challenge. Here, probiotics …