Cardiovascular disease and COVID-19: a consensus paper from the ESC working group on coronary pathophysiology & microcirculation, ESC working group on …
The cardiovascular system is significantly affected in coronavirus disease-19 (COVID-19).
Microvascular injury, endothelial dysfunction, and thrombosis resulting from viral infection or …
Microvascular injury, endothelial dysfunction, and thrombosis resulting from viral infection or …
Federated learning for healthcare domain-pipeline, applications and challenges
Federated learning is the process of develo** machine learning models over datasets
distributed across data centers such as hospitals, clinical research labs, and mobile devices …
distributed across data centers such as hospitals, clinical research labs, and mobile devices …
Hypoimmunogenic derivatives of induced pluripotent stem cells evade immune rejection in fully immunocompetent allogeneic recipients
Autologous induced pluripotent stem cells (iPSCs) constitute an unlimited cell source for
patient-specific cell-based organ repair strategies. However, their generation and …
patient-specific cell-based organ repair strategies. However, their generation and …
An acute immune response underlies the benefit of cardiac stem cell therapy
Clinical trials using adult stem cells to regenerate damaged heart tissue continue to this
day,, despite ongoing questions of efficacy and a lack of mechanistic understanding of the …
day,, despite ongoing questions of efficacy and a lack of mechanistic understanding of the …
Cardiac fibrosis: Myofibroblast-mediated pathological regulation and drug delivery strategies
Cardiac fibrosis remains an unresolved problem in heart diseases. After initial injury, cardiac
fibroblasts (CFs) are activated and subsequently differentiate into myofibroblasts (myoFbs) …
fibroblasts (CFs) are activated and subsequently differentiate into myofibroblasts (myoFbs) …
[HTML][HTML] Longevity leap: mind the healthspan gap
A Garmany, S Yamada, A Terzic - NPJ Regenerative Medicine, 2021 - nature.com
Life expectancy has increased by three decades since the mid-twentieth century. Parallel
healthspan expansion has however not followed, largely impeded by the pandemic of …
healthspan expansion has however not followed, largely impeded by the pandemic of …
A Phase II study of autologous mesenchymal stromal cells and c‐kit positive cardiac cells, alone or in combination, in patients with ischaemic heart failure: the CCTRN …
Aims CONCERT‐HF is an NHLBI‐sponsored, double‐blind, placebo‐controlled, Phase II
trial designed to determine whether treatment with autologous bone marrow‐derived …
trial designed to determine whether treatment with autologous bone marrow‐derived …
Cell therapy trials for heart regeneration—lessons learned and future directions
P Menasché - Nature Reviews Cardiology, 2018 - nature.com
The effects of cell therapy on heart regeneration in patients with chronic cardiomyopathy
have been assessed in several clinical trials. These trials can be categorized as those using …
have been assessed in several clinical trials. These trials can be categorized as those using …
Stem cells in the treatment of disease
HM Blau, GQ Daley - New England Journal of Medicine, 2019 - Mass Medical Soc
Stem-Cell Research and Clinical Application Stem cells have been the focus of hope, hype,
and a great deal of research. But what exactly is a stem cell, and what are its uses? This …
and a great deal of research. But what exactly is a stem cell, and what are its uses? This …
Clinical studies of cell therapy in cardiovascular medicine: recent developments and future directions
Given the rising prevalence of cardiovascular disease worldwide and the limited therapeutic
options for severe heart failure, novel technologies that harness the regenerative capacity of …
options for severe heart failure, novel technologies that harness the regenerative capacity of …