Pathobiology of Helicobacter pylori–induced gastric cancer

M Amieva, RM Peek Jr - Gastroenterology, 2016 - Elsevier
Colonization of the human stomach by Helicobacter pylori and its role in causing gastric
cancer is one of the richest examples of a complex relationship among human cells …

Intestinal permeation enhancers for oral peptide delivery

S Maher, RJ Mrsny, DJ Brayden - Advanced drug delivery reviews, 2016 - Elsevier
Intestinal permeation enhancers (PEs) are one of the most widely tested strategies to
improve oral delivery of therapeutic peptides. This article assesses the intestinal permeation …

Helicobacter pylori and Gastric Cancer: Factors That Modulate Disease Risk

LE Wroblewski, RM Peek Jr… - Clinical microbiology …, 2010 - journals.asm.org
Helicobacter pylori is a gastric pathogen that colonizes approximately 50% of the world's
population. Infection with H. pylori causes chronic inflammation and significantly increases …

Beyond the stomach: an updated view of Helicobacter pylori pathogenesis, diagnosis, and treatment

TL Testerman, J Morris - World journal of gastroenterology …, 2014 - pmc.ncbi.nlm.nih.gov
Helicobacter pylori (H. pylori) is an extremely common, yet underappreciated, pathogen that
is able to alter host physiology and subvert the host immune response, allowing it to persist …

[HTML][HTML] Helicobacter pylori persistence: biology and disease

MJ Blaser, JC Atherton - The Journal of clinical investigation, 2004 - jci.org
Helicobacter pylori are bacteria that have coevolved with humans to be transmitted from
person to person and to persistently colonize the stomach. Their population structure is a …

Host-bacterial interactions in Helicobacter pylori infection

MR Amieva, EM El–Omar - Gastroenterology, 2008 - Elsevier
Helicobacter pylori are spiral-shaped gram-negative bacteria with polar flagella that live
near the surface of the human gastric mucosa. They have evolved intricate mechanisms to …

Helicobacter pylori Virulence and Genetic Geography

A Covacci, JL Telford, GD Giudice, J Parsonnet… - Science, 1999 - science.org
Isolated for the first time in 1982 from human gastric biopsy, Helicobacter pylori is
responsible for gastritis, peptic ulcer, and gastric cancer. A pathogenicity island acquired by …

Type V protein secretion pathway: the autotransporter story

IR Henderson, F Navarro-Garcia… - Microbiology and …, 2004 - journals.asm.org
Gram-negative bacteria possess an outer membrane layer which constrains uptake and
secretion of solutes and polypeptides. To overcome this barrier, bacteria have developed …

THE PATHOGENESIS OF HELICOBACTER PYLORI–INDUCED GASTRO-DUODENAL DISEASES

JC Atherton - Annu. Rev. Pathol. Mech. Dis., 2006 - annualreviews.org
Helicobacter pylori is the main cause of peptic ulceration, distal gastric adenocarcinoma,
and gastric lymphoma. Only 15% of those colonized develop disease, and pathogenesis …

Bacteria and host interactions in the gut epithelial barrier

H Ashida, M Ogawa, M Kim, H Mimuro… - Nature chemical …, 2012 - nature.com
The gut mucosa acts as a barrier against microbial invaders, whereas resident commensal
and foreign invading bacteria interact intimately with the gut epithelium and influence the …