Central regulation of stress-evoked peripheral immune responses

KL Chan, WC Poller, FK Swirski… - Nature Reviews …, 2023 - nature.com
Stress-linked psychiatric disorders, including anxiety and major depressive disorder, are
associated with systemic inflammation. Recent studies have reported stress-induced …

Neurobiological basis of stress resilience

EJ Nestler, SJ Russo - Neuron, 2024 - cell.com
A majority of humans faced with severe stress maintain normal physiological and behavioral
function, a process referred to as resilience. Such stress resilience has been modeled in …

Circulating myeloid-derived MMP8 in stress susceptibility and depression

F Cathomas, HY Lin, KL Chan, L Li, LF Parise… - Nature, 2024 - nature.com
Psychosocial stress has profound effects on the body, including the immune system and the
brain,. Although a large number of pre-clinical and clinical studies have linked peripheral …

[HTML][HTML] Characterizing the mechanisms of social connection

MR Delgado, DS Fareri, LJ Chang - Neuron, 2023 - cell.com
Understanding how individuals form and maintain strong social networks has emerged as a
significant public health priority as a result of the increased focus on the epidemic of …

Cellular and circuit architecture of the lateral septum for reward processing

G Chen, S Lai, S Jiang, F Li, K Sun, X Wu, K Zhou… - Neuron, 2024 - cell.com
The lateral septum (LS) is composed of heterogeneous cell types that are important for
various motivated behaviors. However, the transcriptional profiles, spatial arrangement …

Advancing preclinical chronic stress models to promote therapeutic discovery for human stress disorders

TM Gyles, EJ Nestler, EM Parise - Neuropsychopharmacology, 2024 - nature.com
There is an urgent need to develop more effective treatments for stress-related illnesses,
which include depression, post-traumatic stress disorder, and anxiety. We view animal …

[HTML][HTML] Advancing social behavioral neuroscience by integrating ethology and comparative psychology methods through machine learning

J Bordes, L Miranda, B Müller-Myhsok… - … & Biobehavioral Reviews, 2023 - Elsevier
Social behavior is naturally occurring in vertebrate species, which holds a strong
evolutionary component and is crucial for the normal development and survival of …

Stress, associative learning, and decision-making

J Giovanniello, C Bravo-Rivera, A Rosenkranz… - Neurobiology of learning …, 2023 - Elsevier
Exposure to acute and chronic stress has significant effects on the basic mechanisms of
associative learning and memory. Stress can both impair and enhance associative learning …

[HTML][HTML] Lateral septum as a possible regulatory center of maternal behaviors

G Puska, V Szendi, A Dobolyi - Neuroscience & Biobehavioral Reviews, 2024 - Elsevier
The lateral septum (LS) is involved in controlling anxiety, aggression, feeding, and other
motivated behaviors. Lesion studies have also implicated the LS in various forms of caring …

Distinct circuits and molecular targets of the paraventricular hypothalamus decode visceral and somatic pain

YC Li, FC Zhang, D Li, RX Weng, Y Yu, R Gao, GY Xu - Neuron, 2024 - cell.com
Visceral and somatic pain serve as protective mechanisms against external threats.
Accumulated evidence has confirmed that the paraventricular hypothalamus (PVH) plays an …