Raman spectroscopy is an increasingly popular technique in many areas, including biology
and medicine. It is based on Raman scattering, a phenomenon in which incident photons …

High-throughput methods for slide-free three-dimensional (3D) pathological analyses of
whole biopsies and surgical specimens offer the promise of modernizing traditional …

The histological analysis of tissue samples, widely used for disease diagnosis, involves
lengthy and laborious tissue preparation. Here, we show that a convolutional neural network …

Human tissue, which is inherently three-dimensional (3D), is traditionally examined through
standard-of-care histopathology as limited two-dimensional (2D) cross-sections that can …

For the 1.7 million patients per year in the US who receive a new cancer diagnosis,
treatment decisions are largely based on histopathological specimen examinations …

Intravital microscopy (IVM) emerged and matured as a powerful tool for elucidating
pathways in biological processes. Although label-free multiphoton IVM is attractive for its …

Histological staining is a vital step in diagnosing various diseases and has been used for
more than a century to provide contrast in tissue sections, rendering the tissue constituents …

Holotomography (HT) represents a 3D, label-free optical imaging methodology that
leverages refractive index as an inherent quantitative contrast for imaging. This technique …

Traditional histochemical staining of post-mortem samples often confronts inferior staining
quality due to autolysis caused by delayed fixation of cadaver tissue, and such chemical …

The physics and applications of fiber-based supercontinuum (SC) sources have been a
subject of intense interest over the last decade, with significant impact on both basic science …