Declining locus coeruleus–dopaminergic and noradrenergic modulation of long-term memory in aging and Alzheimer's disease

MJ Dahl, A Kulesza, M Werkle-Bergner… - … & Biobehavioral Reviews, 2023 - Elsevier
Memory is essential in defining our identity by guiding behavior based on past experiences.
However, aging leads to declining memory, disrupting older adult's lives. Memories are …

Revealing visual working memory operations with pupillometry: Encoding, maintenance, and prioritization

D Koevoet, C Strauch… - Wiley …, 2024 - Wiley Online Library
Pupillary dynamics reflect effects of distinct and important operations of visual working
memory: encoding, maintenance, and prioritization. Here, we review how pupil size predicts …

Phasic, event-related transcutaneous auricular vagus nerve stimulation modifies behavioral, pupillary, and low-frequency oscillatory power responses

C Wienke, M Grueschow, A Haghikia… - Journal of …, 2023 - Soc Neuroscience
Transcutaneous auricular vagus nerve stimulation (taVNS) has been proposed to activate
the locus ceruleus-noradrenaline (LC-NA) system. However, previous studies failed to find …

Rhythms in cognition: The evidence revisited

C Keitel, M Ruzzoli, L Dugué, NA Busch… - European Journal of …, 2022 - Wiley Online Library
Eur J Neurosci. 2022; 55: 2991–3009. wileyonlinelibrary. com/journal/ejn 2991 and with a
certain strength or amplitude (Figure 1). Attempts to account for the functional relevance of …

Coupling of pupil-and neuronal population dynamics reveals diverse influences of arousal on cortical processing

T Pfeffer, C Keitel, DS Kluger, A Keitel, A Russmann… - elife, 2022 - elifesciences.org
Fluctuations in arousal, controlled by subcortical neuromodulatory systems, continuously
shape cortical state, with profound consequences for information processing. Yet, how …

Neuromodulation of neural oscillations in health and disease

E Weiss, M Kann, Q Wang - Biology, 2023 - mdpi.com
Simple Summary Over the past few decades, advances in electroencephalography (EEG)
recordings and brain stimulation has permitted an unprecedented view of how specific brain …

Neuronal activity in the human amygdala and hippocampus enhances emotional memory encoding

SE Qasim, UR Mohan, JM Stein, J Jacobs - Nature Human Behaviour, 2023 - nature.com
Emotional events comprise our strongest and most valuable memories. Here we examined
how the brain prioritizes emotional information for storage using direct brain recording and …

Role of the locus coeruleus and basal forebrain in arousal and attention

EB Maness, JA Burk, JT McKenna, FL Schiffino… - Brain research …, 2022 - Elsevier
Experimental evidence has implicated multiple neurotransmitter systems in either the direct
or indirect modulation of cortical arousal and attention circuitry. In this review, we selectively …

Cognitive and neuropsychiatric effects of noradrenergic treatment in Alzheimer's disease: systematic review and meta-analysis

MCB David, M Del Giovane, KY Liu… - Journal of Neurology …, 2022 - jnnp.bmj.com
Background Dysfunction of the locus coeruleus-noradrenergic system occurs early in
Alzheimer's disease, contributing to cognitive and neuropsychiatric symptoms in some …

The integrity of dopaminergic and noradrenergic brain regions is associated with different aspects of late-life memory performance

MJ Dahl, SL Bachman, S Dutt, S Düzel, NC Bodammer… - Nature Aging, 2023 - nature.com
Abstract Changes in dopaminergic neuromodulation play a key role in adult memory
decline. Recent research has also implicated noradrenaline in sha** late-life memory …