Publisher Summary This chapter reviews the histopathologic, serologic, lymphocytic,
virological, hormonal, and genetic characteristics of murine models of systemic lupus …

At no time in recent memory has it been so difficult to offer succint generalizations about the
biology of the mast cell, or its role in health and disease. This situation is something of a …

Organ-specific autoimmune diseases such as oophoritis, gastritis, thyroiditis, and orchitis
were induced in female or male nude (nu/nu) mice by the transfer of nu/+ spleen cells from …

A cDNA clone encoding a novel hematopoietic growth factor activity produced by a gibbon T
cell line has been identified using a mammalian cell expression cloning system. The …

Clones of complementary DNA encoding the human lymphokine known as granulocyte-
macrophage colony-stimulating factor (GM-CSF) were isolated by means of a mammalian …

Complementary DNA (cDNA) clones encoding human macrophage-specific colony-
stimulating factor (CSF-1) were isolated. One cDNA clone codes for a mature polypeptide of …

The pathogenesis of ocular allergy involves multiple mechanisms, which lead to mast cell
degranulation and the release of chemical mediators. Mast cell mediators that have been …

The cDNA sequence for murine interleukin-3, one of the colony stimulating factors that
regulate haematopoiesis, codes for a polypeptide of 166 amino acids including a putative …

We previously reported that transforming growth factor beta (TGF-beta) selectively inhibits
colony-stimulating factor-driven hematopoietic progenitor cell growth. We report here that …

Since the original description by Paul Ehrlich, mast cells have been recognized by their
large, electrondense cytoplasmic granules containing metachromatitally staining …