The post‐translational regulation of transcription factor EB (TFEB) in health and disease

M Takla, S Keshri, DC Rubinsztein - EMBO reports, 2023 - embopress.org
Transcription factor EB (TFEB) is a basic helix–loop–helix leucine zipper transcription factor
that acts as a master regulator of lysosomal biogenesis, lysosomal exocytosis, and macro …

Membrane remodeling and trafficking piloted by SARS-CoV-2

MC Sergio, S Ricciardi, AM Guarino, L Giaquinto… - Trends in Cell …, 2024 - cell.com
The molecular mechanisms underlying SARS-CoV-2 host cell invasion and life cycle have
been studied extensively in recent years, with a primary focus on viral entry and …

TFEB and TFE3 cooperate in regulating inorganic arsenic-induced autophagy-lysosome impairment and immuno-dysfunction in primary dendritic cells

G Xu, H Peng, R Yao, Y Yang, B Li - Cell Biology and Toxicology, 2024 - Springer
Arsenic (As) is a prevalent and hazardous environmental toxicant associated with cancer
and various health problems, which has been shown suppressive effects on dendritic cells …

Baculovirus protein kinase 1 activates AMPK-protein phosphatase 5 axis to hijack transcription factor EB for self-proliferation

J Pan, X Li, R Li, Y Chen, FU Memon, K Wu… - International Journal of …, 2025 - Elsevier
Baculovirus causes lethal nuclear polyhedrosis in insects, whereas its regulatory
mechanism on host transcription has not been fully illustrated. Herein, Bombyx mori …

Neurodegenerative diseases reflect the reciprocal roles played by retroelements in regulating memory and immunity

A Herbert - Frontiers in Neuroscience, 2024 - frontiersin.org
Tetrapod endogenous retroelements (ERE) encode proteins that have been exapted to
perform many roles in development and also in innate immunity, including GAG (group …