[HTML][HTML] Oxidative cysteine post translational modifications drive the redox code underlying neurodegeneration and amyotrophic lateral sclerosis
A Percio, M Cicchinelli, D Masci, M Summo, A Urbani… - Antioxidants, 2024 - mdpi.com
Redox dysregulation, an imbalance between oxidants and antioxidants, is crucial in the
pathogenesis of various neurodegenerative diseases. Within this context, the “redoxome” …
pathogenesis of various neurodegenerative diseases. Within this context, the “redoxome” …
Current Technologies Unraveling the Significance of Post-Translational Modifications (PTMs) as Crucial Players in Neurodegeneration
S Zafar, SI Fatima, M Schmitz, I Zerr - Biomolecules, 2024 - mdpi.com
Neurodegenerative disorders, such as Parkinson's disease, Alzheimer's disease, and
Huntington's disease, are identified and characterized by the progressive loss of neurons …
Huntington's disease, are identified and characterized by the progressive loss of neurons …
Neuroinflammation at the crossroads of metabolic and neurodegenerative diseases: Causes, consequences and interventions.
Neuroinflammation is increasingly recognized as a pivotal factor not only in
neurodegenerative diseases such as Alzheimer's and Parkinson's, but also in the …
neurodegenerative diseases such as Alzheimer's and Parkinson's, but also in the …
Exploring Natural Compounds as Potential CDK4 Inhibitors for Therapeutic Intervention in Neurodegenerative Diseases through Computational Analysis
CDK4 is a member of the serine-threonine kinase family, which has been found to be
overexpressed in a plethora of studies related to neurodegenerative diseases. CDK4 is one …
overexpressed in a plethora of studies related to neurodegenerative diseases. CDK4 is one …
PTMs of PD-1/PD-L1 and PROTACs application for improving cancer immunotherapy
X Ren, L Wang, L Liu, J Liu - Frontiers in Immunology, 2024 - frontiersin.org
Immunotherapy has been developed, which harnesses and enhances the innate powers of
the immune system to fight disease, particularly cancer. PD-1 (programmed death-1) and PD …
the immune system to fight disease, particularly cancer. PD-1 (programmed death-1) and PD …
The main sources of molecular organization in the cell. Atlas of self-organized and self-regulated dynamic biostructures
One of the most important goals of contemporary biology is to understand the principles of
the molecular order underlying the complex dynamic architecture of cells. Here, we present …
the molecular order underlying the complex dynamic architecture of cells. Here, we present …
[HTML][HTML] O-GlcNAcylation in ovarian tumorigenesis and its therapeutic implications
L **a, J Mei, M Huang, D Bao, Z Wang, Y Chen - Translational Oncology, 2025 - Elsevier
Ovarian cancer is a prevalent malignancy among women, often associated with a poor
prognosis. Post-translational modifications (PTMs), particularly O-GlcNAcylation, have been …
prognosis. Post-translational modifications (PTMs), particularly O-GlcNAcylation, have been …
A Comprehensive Review on Molecular Mechanisms, Treatments, and Brief Role of Natural Products in Hepatocellular Cancer
L Jiang, Q Meng, L Liu, W Li - Natural Product …, 2024 - journals.sagepub.com
Most initial liver cancers are hepatocellular carcinomas (HCC), which make up the vast
majority of cases. Hepatitis B or C virus infection as well as alcohol consumption is among …
majority of cases. Hepatitis B or C virus infection as well as alcohol consumption is among …
[PDF][PDF] Pazopanib: Effective monotherapy for precise cancer treatment, targeting specific mutations and tumors
Cancer is a wide range of illnesses characterized by the expansion of abnormal cells with
the ability to invade and damage healthy bodily tissue. Cancer is treated with a variety of …
the ability to invade and damage healthy bodily tissue. Cancer is treated with a variety of …
Histone methylation and acetylation in cancer: mechanism, progression, and targets
S Bu, T Ye, H Gao, H Song, Y Zhu - Oncologie, 2024 - degruyter.com
Along with the continuous development of chromatin immunoprecipitation sequencing and
its derivative technologies, as well as an increased understanding of epigenetic …
its derivative technologies, as well as an increased understanding of epigenetic …