Theranostic fluorescent probes

A Sharma, P Verwilst, M Li, D Ma, N Singh… - Chemical …, 2024 - ACS Publications
The ability to gain spatiotemporal information, and in some cases achieve spatiotemporal
control, in the context of drug delivery makes theranostic fluorescent probes an attractive …

Precise modulation and use of reactive oxygen species for immunotherapy

X Li, J Gao, C Wu, C Wang, R Zhang, J He, ZJ **a… - Science …, 2024 - science.org
Reactive oxygen species (ROS) play an important role in regulating the immune system by
affecting pathogens, cancer cells, and immune cells. Recent advances in biomaterials have …

Stem cell‐derived Nanovesicles embedded in dual‐layered hydrogel for programmed ROS regulation and comprehensive tissue regeneration in burn wound healing

M Zhao, M Kang, J Wang, R Yang, X Zhong… - Advanced …, 2024 - Wiley Online Library
Burn wounds often bring high risks of delayed healing process and even death. Reactive
oxygen species (ROS) play a crucial role in burn wound repair. However, the dynamic …

Smart biomaterials for articular cartilage repair and regeneration

Z Gu, J Wang, Y Fu, H Pan, H He… - Advanced Functional …, 2023 - Wiley Online Library
Articular cartilage defects bring about disability and worldwide socioeconomic loss,
therefore, articular cartilage repair and regeneration is recognized as a global issue …

Mitochondria-specific drug release and reactive oxygen species burst induced by polyprodrug nanoreactors can enhance chemotherapy

W Zhang, X Hu, Q Shen, D **ng - Nature communications, 2019 - nature.com
Cancer cells exhibit slightly elevated levels of reactive oxygen species (ROS) compared with
normal cells, and approximately 90% of intracellular ROS is produced in mitochondria. In …

Small‐molecule prodrug nanoassemblies: an emerging nanoplatform for anticancer drug delivery

G Li, B Sun, Y Li, C Luo, Z He, J Sun - Small, 2021 - Wiley Online Library
The antitumor efficiency and clinical translation of traditional nanomedicines is mainly
restricted by low drug loading, complex preparation technology, and potential toxicity …

Red-light-triggered self-destructive mesoporous silica nanoparticles for cascade-amplifying chemo-photodynamic therapy favoring antitumor immune responses

Y Yang, F Chen, N Xu, Q Yao, R Wang, X **e, F Zhang… - Biomaterials, 2022 - Elsevier
Although chemo-photodynamic therapy demonstrates promising synergetic therapeutic
effects in malignant tumors, the light-controlled drug release, synergism and biocompatibility …

Light: a magical tool for controlled drug delivery

Y Tao, HF Chan, B Shi, M Li… - Advanced Functional …, 2020 - Wiley Online Library
Light is a particularly appealing tool for on‐demand drug delivery due to its noninvasive
nature, ease of application, and exquisite temporal and spatial control. Great progress is …

Nanomedicines for reactive oxygen species mediated approach: an emerging paradigm for cancer treatment

S Kwon, H Ko, DG You, K Kataoka… - Accounts of Chemical …, 2019 - ACS Publications
Conspectus Growth in the knowledge of cancer biology has led to the emergence and
evolution of cancer nanomedicines by providing the rationale for leveraging nanotechnology …

Photoactivatable protherapeutic nanomedicine for cancer

Y Zhang, C Xu, X Yang, K Pu - Advanced Materials, 2020 - Wiley Online Library
Therapeutic systems with site‐specific pharmaceutical activation hold great promise to
enhance therapeutic efficacy while reducing systemic toxicity in cancer therapy. With …