Gut microbial antigenic mimicry in autoimmunity

N Garabatos, P Santamaria - Frontiers in Immunology, 2022 - frontiersin.org
The gut microbiota plays a major role in the developmental biology and homeostasis of cells
belonging to the adaptive and innate arms of the immune system. Alterations in its …

T‐cell activation–induced marker assays in health and disease

C Poloni, C Schonhofer, S Ivison… - … and Cell Biology, 2023 - Wiley Online Library
Activation‐induced marker (AIM) assays have proven to be an accessible and rapid means
of antigen‐specific T‐cell detection. The method typically involves short‐term incubation of …

[HTML][HTML] CXCR3-expressing T cells in infections and autoimmunity

A Rubinstein, I Kudryavtsev, N Arsentieva… - Frontiers in Bioscience …, 2024 - imrpress.com
The chemokine receptor CXCR3 and its ligands (MIG/CXCL9, IP-10/CXCL10, and I-
TAC/CXCL11) play a central role in the generation of cellular inflammation, both in the …

Crohn's disease patients uniquely contain inflammatory responses to flagellin in a CD4 effector memory subset

NN Morgan, LW Duck, J Wu, M Rujani… - Inflammatory bowel …, 2022 - academic.oup.com
Background Specific microbial antigens stimulate production of antibodies indicative of the
aberrant immune response in Crohn's disease (CD). We tested for T cell reactivity linkage to …

[HTML][HTML] Overview of the microbiota in the gut-liver axis in viral B and C hepatitis

MA Neag, AO Mitre, A Catinean… - World Journal of …, 2021 - ncbi.nlm.nih.gov
Viral B and C hepatitis are a major current health issue, both diseases having a chronic
damaging effect on the liver and its functions. Chronic liver disease can lead to even more …