Lyme disease in humans

JD Radolf, K Strle, JE Lemieux, F Strle - Current issues in molecular …, 2021 - mdpi.com
Lyme disease (Lyme borreliosis) is a tick-borne, zoonosis of adults and children caused by
genospecies of the Borrelia burgdorferi sensu lato complex. The ailment, widespread …

Genomics of Actinobacteria: Tracing the Evolutionary History of an Ancient Phylum

M Ventura, C Canchaya, A Tauch… - Microbiology and …, 2007 - Am Soc Microbiol
Actinobacteria constitute one of the largest phyla among Bacteria and represent gram-
positive bacteria with a high G+ C content in their DNA. This bacterial group includes …

Phylogenies of the 16S rRNA gene and its hypervariable regions lack concordance with core genome phylogenies

HB Hassler, B Probert, C Moore, E Lawson… - Microbiome, 2022 - Springer
Abstract Background The 16S rRNA gene is used extensively in bacterial phylogenetics, in
species delineation, and now widely in microbiome studies. However, the gene suffers from …

Modeling site heterogeneity with posterior mean site frequency profiles accelerates accurate phylogenomic estimation

HC Wang, BQ Minh, E Susko, AJ Roger - Systematic biology, 2018 - academic.oup.com
Proteins have distinct structural and functional constraints at different sites that lead to site-
specific preferences for particular amino acid residues as the sequences evolve …

BMGE (Block Map** and Gathering with Entropy): a new software for selection of phylogenetic informative regions from multiple sequence alignments

A Criscuolo, S Gribaldo - BMC evolutionary biology, 2010 - Springer
Background The quality of multiple sequence alignments plays an important role in the
accuracy of phylogenetic inference. It has been shown that removing ambiguously aligned …

Relaxed phylogenetics and dating with confidence

AJ Drummond, SYW Ho, MJ Phillips, A Rambaut - PLoS biology, 2006 - journals.plos.org
In phylogenetics, the unrooted model of phylogeny and the strict molecular clock model are
two extremes of a continuum. Despite their dominance in phylogenetic inference, it is …

Towards a genome-based taxonomy for prokaryotes

KT Konstantinidis, JM Tiedje - Journal of bacteriology, 2005 - Am Soc Microbiol
The ranks higher than the species in the prokaryotic taxonomy are primarily designated
based on phylogenetic analysis of the 16S rRNA gene sequences, but no definite standards …

The human gut and groundwater harbor non-photosynthetic bacteria belonging to a new candidate phylum sibling to Cyanobacteria

SC Di Rienzi, I Sharon, KC Wrighton, O Koren, LA Hug… - elife, 2013 - elifesciences.org
Cyanobacteria were responsible for the oxygenation of the ancient atmosphere; however,
the evolution of this phylum is enigmatic, as relatives have not been characterized. Here we …

Mesophilic Crenarchaeota: proposal for a third archaeal phylum, the Thaumarchaeota

C Brochier-Armanet, B Boussau, S Gribaldo… - Nature Reviews …, 2008 - nature.com
The archaeal domain is currently divided into two major phyla, the Euryarchaeota and
Crenarchaeota. During the past few years, diverse groups of uncultivated mesophilic …

Bacterial genome instability

E Darmon, DRF Leach - Microbiology and Molecular Biology …, 2014 - Am Soc Microbiol
Bacterial genomes are remarkably stable from one generation to the next but are plastic on
an evolutionary time scale, substantially shaped by horizontal gene transfer, genome …