Structure, function and drug discovery of GPCR signaling
L Cheng, F ** modulatory antibodies against G protein-coupled receptors is challenging. In
this study, we targeted the follicle-stimulating hormone receptor (FSHR), a significant …
this study, we targeted the follicle-stimulating hormone receptor (FSHR), a significant …
Functional dynamics of G protein-coupled receptors reveal new routes for drug discovery
G protein-coupled receptors (GPCRs) are the largest human membrane protein family that
transduce extracellular signals into cellular responses. They are major pharmacological …
transduce extracellular signals into cellular responses. They are major pharmacological …
Cryo-electron microscopy for GPCR research and drug discovery in endocrinology and metabolism
G protein-coupled receptors (GPCRs) are the largest family of cell surface receptors, with
many GPCRs having crucial roles in endocrinology and metabolism. Cryogenic electron …
many GPCRs having crucial roles in endocrinology and metabolism. Cryogenic electron …