Antiretroviral therapy of HIV infection has changed a uniformly fatal into a potentially chronic
disease. There are now 17 drugs in common use for HIV treatment. Patients who can access …

Background Antiretroviral drugs reduce viral replication and can reduce mother‐to‐child
transmission of HIV either by lowering plasma viral load in pregnant women or through post …

Cardiovascular disease now ranks as the world's top cause of death, causing one third of all
deaths globally. Heart disease can no longer be seen as the problem of overworked and …

ABSTRACT HIV-infected infants frequently present with clinical symptoms in the first year of
life. Without effective treatment, an estimated one third of infected infants will have died by …

The most up-to-date estimates demonstrate very heterogeneous spread of HIV-1, and more
than 30 million people are now living with HIV-1 infection, most of them in sub-Saharan …

Despite advances in antiretroviral therapy that have revolutionized HIV disease
management, effective control of the HIV infection pandemic remains elusive. Beyond the …

Background In 1999, we reported safety and efficacy data for short-course nevirapine from a
Ugandan perinatal HIV-1 prevention trial when 496 babies were followed up to age 14–16 …

Background Although zidovudine prophylaxis decreases the rate of transmission of the
human immunodeficiency virus (HIV) type 1 substantially, a large number of infants still …

New information about the benefits and limitations of testing for resistance to human
immunodeficiency virus (HIV) type 1 (HIV-1) drugs has emerged. The International AIDS …

ContextA 2-dose intrapartum/newborn nevirapine regimen reduced perinatal human
immunodeficiency virus (HIV) transmission in Ugandan women not receiving antenatal …