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In situ nucleic acid sequencing of expanded biological samples
US10059990B2 - In situ nucleic acid sequencing of expanded biological samples - Google
Patents US10059990B2 - In situ nucleic acid sequencing of expanded biological samples …
Patents US10059990B2 - In situ nucleic acid sequencing of expanded biological samples …
Nucleic acid sequencing
T Hauling, M Kühnemund - US Patent 11,352,667, 2022 - Google Patents
(57) ABSTRACT A nucleic acid sequencing method involving contacting a spatially defined
target nucleic acid sequence with N labeled oligonucleotide probes and performing …
target nucleic acid sequence with N labeled oligonucleotide probes and performing …
RNA templated ligation
M Nilsson, M Kühnemund, T Krzywkowski - US Patent 11,597,965, 2023 - Google Patents
the present invention relates to the field of nucleic acid detection. Specifically, the present
invention provides methods for detecting target nucleic acid sequences in a target nucleic …
invention provides methods for detecting target nucleic acid sequences in a target nucleic …
Nanoscale imaging of proteins and nucleic acids via expansion microscopy
2016-10-03 Assigned to MASSACHUSETTS INSTITUTE OF TECHNOLOGY reassignment
MASSACHUSETTS INSTITUTE OF TECHNOLOGY ASSIGNMENT OF ASSIGNORS …
MASSACHUSETTS INSTITUTE OF TECHNOLOGY ASSIGNMENT OF ASSIGNORS …
Protein retention expansion microscopy
2016-10-03 Assigned to MASSACHUSETTS INSTITUTE OF TECHNOLOGY reassignment
MASSACHUSETTS INSTITUTE OF TECHNOLOGY ASSIGNMENT OF ASSIGNORS …
MASSACHUSETTS INSTITUTE OF TECHNOLOGY ASSIGNMENT OF ASSIGNORS …
Iterative expansion microscopy
The present invention leverages the techniques for expan sion microscopy (ExM) to provide
improved high-through put super-resolution whole-organ imaging methodology to image …
improved high-through put super-resolution whole-organ imaging methodology to image …
Hybridization chain reaction methods for in situ molecular detection
2019-02-06 Assigned to PRESIDENT AND FELLOWS OF HARVARD COLLEGE
reassignment PRESIDENT AND FELLOWS OF HARVARD COLLEGE ASSIGNMENT OF …
reassignment PRESIDENT AND FELLOWS OF HARVARD COLLEGE ASSIGNMENT OF …
In situ ATAC sequencing
The present invention provides methods for analyzing poly nucleotides such as genomic
DNA. In some embodiments, the disclosure provides a method for preparing and ampli fying …
DNA. In some embodiments, the disclosure provides a method for preparing and ampli fying …
Methods and compositions for integrated in situ spatial assay
FA Bava, Z Bent - US Patent 12,173,360, 2024 - Google Patents
JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-
oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo …
oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo …
Augmenting in situ nucleic acid sequencing of expanded biological samples with in vitro sequence information
2005/0034990 Al 2005/0090016 A1 2005/0169962 A1 2005/0196702 A1 2006/0000767 Al
2006/0003356 A1 2006/0110760 Al 2006/0115146 Al 2006/0165912 A1 2007/0023942 A1 …
2006/0003356 A1 2006/0110760 Al 2006/0115146 Al 2006/0165912 A1 2007/0023942 A1 …