Early detection of cancer
Survival improves when cancer is detected early. However,~ 50% of cancers are at an
advanced stage when diagnosed. Early detection of cancer or precancerous change allows …
advanced stage when diagnosed. Early detection of cancer or precancerous change allows …
International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma
Summary This International Myeloma Working Group consensus updates the disease
definition of multiple myeloma to include validated biomarkers in addition to existing …
definition of multiple myeloma to include validated biomarkers in addition to existing …
Multiple myeloma: 2022 update on diagnosis, risk stratification, and management
SV Rajkumar - American journal of hematology, 2022 - Wiley Online Library
Abstract Disease Overview Multiple myeloma accounts for approximately 10% of
hematologic malignancies. Diagnosis The diagnosis requires≥ 10% clonal bone marrow …
hematologic malignancies. Diagnosis The diagnosis requires≥ 10% clonal bone marrow …
Clonal hematopoiesis of indeterminate potential and its distinction from myelodysplastic syndromes
Recent genetic analyses of large populations have revealed that somatic mutations in
hematopoietic cells leading to clonal expansion are commonly acquired during human …
hematopoietic cells leading to clonal expansion are commonly acquired during human …
Long-term follow-up of monoclonal gammopathy of undetermined significance
RA Kyle, DR Larson, TM Therneau… - New England journal …, 2018 - Mass Medical Soc
Background Monoclonal gammopathy of undetermined significance (MGUS) occurs in
approximately 3% of persons 50 years of age or older. Methods We studied 1384 patients …
approximately 3% of persons 50 years of age or older. Methods We studied 1384 patients …
The evaluation of monoclonal gammopathy of renal significance: a consensus report of the International Kidney and Monoclonal Gammopathy Research Group
The term monoclonal gammopathy of renal significance (MGRS) was introduced by the
International Kidney and Monoclonal Gammopathy Research Group (IKMG) in 2012. The …
International Kidney and Monoclonal Gammopathy Research Group (IKMG) in 2012. The …
Multiple myeloma: diagnosis and treatment
The diagnosis and treatment of multiple myeloma has changed dramatically in the past
decade. The disease definition has been updated to include highly specific biomarkers in …
decade. The disease definition has been updated to include highly specific biomarkers in …
International myeloma working group consensus recommendations on imaging in monoclonal plasma cell disorders
Recent advances in the treatment of multiple myeloma have increased the need for accurate
diagnosis of the disease. The detection of bone and bone marrow lesions is crucial in the …
diagnosis of the disease. The detection of bone and bone marrow lesions is crucial in the …
Aging and the immune system: An overview
AAS Akha - Journal of immunological methods, 2018 - Elsevier
The world is witnessing a rapid demographic shift towards an older population, a trend with
major medical, social, economic and political implications. Aging is a multifaceted process …
major medical, social, economic and political implications. Aging is a multifaceted process …
Monoclonal gammopathy of undetermined significance (MGUS) consistently precedes multiple myeloma: a prospective study
Monoclonal gammopathy of undetermined significance (MGUS) is a premalignant plasma-
cell proliferative disorder associated with a life-long risk of progression to multiple myeloma …
cell proliferative disorder associated with a life-long risk of progression to multiple myeloma …