Owing to a growing awareness towards environmental impact, the search for “greener”,
safer, and cost-effective solvents able to replace petroleum-derived solvents has never been …

Rheumatoid arthritis, arthrosis and gout, among other chronic inflammatory diseases are
public health problems and represent major therapeutic challenges. Non-steroidal anti …

A series of new heterocycle hybrids incorporating pyrazole and isoxazoline rings was
successfully synthesized, characterized, and evaluated for their antimicrobial responses …

Abstract β-Carboline alkaloids are a family of natural and synthetic products with structural
diversity and outstanding antitumor activities. This review summarizes research …

Isoxazoles and isoxazolines are five-membered heterocyclic molecules containing nitrogen
and oxygen. Isoxazole and isoxazoline are the most popular heterocyclic compounds for …

Alzheimer's disease (AD) is a progressive neurodegenerative disease with no clinically
accepted treatment to cure or halt its progression. The Food and Drug Administration has …

Harmine is isolated from the seeds of the medicinal plant, Peganum harmala L., and has
been used for thousands of years in the Middle East and China. Harmine has many …

Isoxazolines are nitrogen‐and oxygen‐containing five‐membered heterocyclic scaffolds
with extensive biological activities. This framework can be readily obtained in good to …

A novel series of chromone-isoxazoline conjugates was successfully synthesized by the O-
alkylation and 1, 3-dipolar cycloaddition reactions using methyl 7‑hydroxy-4H-chromone-3 …

The natural β-carboline alkaloids display similarities with neurotransmitters that can be
favorably exploited to design bioactive and bioavailable drugs for Alzheimer's disease (AD) …