Optical coherence tomography as retinal imaging biomarker of neuroinflammation/neurodegeneration in systemic disorders in adults and children
The retina and the optic nerve are considered extensions of the central nervous system
(CNS) and thus can serve as the window for evaluation of CNS disorders. Spectral domain …
(CNS) and thus can serve as the window for evaluation of CNS disorders. Spectral domain …
Retinal α-synuclein deposits in Parkinson's disease patients and animal models
L Veys, M Vandenabeele, I Ortuno-Lizaran… - Acta …, 2019 - Springer
Despite decades of research, accurate diagnosis of Parkinson's disease remains a
challenge, and disease-modifying treatments are still lacking. Research into the early …
challenge, and disease-modifying treatments are still lacking. Research into the early …
[HTML][HTML] Machine learning in diagnosis and disability prediction of multiple sclerosis using optical coherence tomography
Background Multiple sclerosis (MS) is a neurodegenerative disease that affects the central
nervous system, especially the brain, spinal cord, and optic nerve. Diagnosis of this disease …
nervous system, especially the brain, spinal cord, and optic nerve. Diagnosis of this disease …
Neurodegeneration in multiple sclerosis: Symptoms of silent progression, biomarkers and neuroprotective therapy—Kynurenines are important players
D Sandi, Z Fricska-Nagy, K Bencsik, L Vécsei - Molecules, 2021 - mdpi.com
Neurodegeneration is one of the driving forces behind the pathogenesis of multiple sclerosis
(MS). Progression without activity, pathopsychological disturbances (cognitive impairment …
(MS). Progression without activity, pathopsychological disturbances (cognitive impairment …
Swept source optical coherence tomography to early detect multiple sclerosis disease. The use of machine learning techniques
Objective To compare axonal loss in ganglion cells detected with swept-source optical
coherence tomography (SS-OCT) in eyes of patients with multiple sclerosis (MS) versus …
coherence tomography (SS-OCT) in eyes of patients with multiple sclerosis (MS) versus …
Early diagnosis of multiple sclerosis by OCT analysis using Cohen's d method and a neural network as classifier
Background The consequences of inflammation, demyelination, axonal degeneration and
neuronal loss in the central nervous system, typical of the development of multiple sclerosis …
neuronal loss in the central nervous system, typical of the development of multiple sclerosis …
Computer-aided diagnosis of multiple sclerosis using a support vector machine and optical coherence tomography features
C Cavaliere, E Vilades, MC Alonso-Rodríguez… - Sensors, 2019 - mdpi.com
The purpose of this paper is to evaluate the feasibility of diagnosing multiple sclerosis (MS)
using optical coherence tomography (OCT) data and a support vector machine (SVM) as an …
using optical coherence tomography (OCT) data and a support vector machine (SVM) as an …
Macular ganglion cell–inner plexiform layer thinning as a biomarker of disability progression in relapsing multiple sclerosis
G Bsteh, K Berek, H Hegen, P Altmann… - Multiple Sclerosis …, 2021 - journals.sagepub.com
Background: Macular ganglion cell–inner plexiform layer (mGCIPL) is an emerging
biomarker of neuroaxonal degeneration in multiple sclerosis (MS). Objective: We aimed to …
biomarker of neuroaxonal degeneration in multiple sclerosis (MS). Objective: We aimed to …
Early diagnosis of multiple sclerosis using swept-source optical coherence tomography and convolutional neural networks trained with data augmentation
A López-Dorado, M Ortiz, M Satue, MJ Rodrigo… - Sensors, 2021 - mdpi.com
Background: The aim of this paper is to implement a system to facilitate the diagnosis of
multiple sclerosis (MS) in its initial stages. It does so using a convolutional neural network …
multiple sclerosis (MS) in its initial stages. It does so using a convolutional neural network …
Recent progress in the identification of early transition biomarkers from relapsing-remitting to progressive multiple sclerosis
Despite extensive research into the pathophysiology of multiple sclerosis (MS) and recent
developments in potent disease-modifying therapies (DMTs), two-thirds of relapsing …
developments in potent disease-modifying therapies (DMTs), two-thirds of relapsing …