Dopamine in Parkinson's disease

S Latif, M Jahangeer, DM Razia, M Ashiq, A Ghaffar… - Clinica chimica acta, 2021 - Elsevier
Parkinson's disease is a neurodegenerative disease caused by the death of neurons, ie,
cells critical to the production of dopamine, an important neurotransmitter in the brain. Here …

Atypical antipsychotics and metabolic syndrome: from molecular mechanisms to clinical differences

M Carli, S Kolachalam, B Longoni, A Pintaudi… - Pharmaceuticals, 2021 - mdpi.com
Atypical antipsychotics (AAPs) are commonly prescribed medications to treat schizophrenia,
bipolar disorders and other psychotic disorders. However, they might cause metabolic …

Therapeutic potential of TAAR1 agonists in schizophrenia: evidence from preclinical models and clinical studies

N Dedic, H Dworak, C Zeni, G Rutigliano… - International Journal of …, 2021 - mdpi.com
Trace amine-associated receptor 1 (TAAR1) has emerged as a promising therapeutic target
for neuropsychiatric disorders due to its ability to modulate monoaminergic and …

The burden of antipsychotic-induced weight gain and metabolic syndrome in children

MR Libowitz, EL Nurmi - Frontiers in Psychiatry, 2021 - frontiersin.org
Antipsychotic medications are critical to child and adolescent psychiatry, from the
stabilization of psychotic disorders like schizophrenia, bipolar disorder, and psychotic …

[HTML][HTML] Data-driven taxonomy for antipsychotic medication: a new classification system

RA McCutcheon, PJ Harrison, OD Howes… - Biological …, 2023 - Elsevier
Background Globally, there are more than 25 licensed antipsychotic medications.
Antipsychotics are commonly described as either typical or atypical, but this dichotomous …

Implications of adverse outcomes associated with antipsychotics in older patients with dementia: a 2011–2022 update

M Rogowska, M Thornton, B Creese, L Velayudhan… - Drugs & Aging, 2023 - Springer
Neuropsychiatric symptoms affect most patients with dementia over the course of the
disease. They include a wide variety of symptoms from apathy and depression to psychosis …

Antipsychotic-induced weight gain: dose-response meta-analysis of randomized controlled trials

H Wu, S Siafis, T Hamza… - Schizophrenia …, 2022 - academic.oup.com
Background Weight gain is among the most important side-effects of antipsychotics. It is,
however, unclear whether it is associated with antipsychotic doses. We aimed to fill this gap …

Non-alcoholic fatty liver disease (NAFLD) and mental illness: Mechanisms linking mood, metabolism and medicines

A Gangopadhyay, R Ibrahim, K Theberge… - Frontiers in …, 2022 - frontiersin.org
Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease
in the world and one of the leading indications for liver transplantation. It is one of the many …

[HTML][HTML] Crosstalk between schizophrenia and metabolic syndrome: The role of oxytocinergic dysfunction

KK Goh, CYA Chen, TH Wu, CH Chen… - International journal of …, 2022 - mdpi.com
The high prevalence of metabolic syndrome in persons with schizophrenia has spurred
investigational efforts to study the mechanism beneath its pathophysiology. Early psychosis …

Effect of exposure to endocrine disrupting chemicals in obesity and neurodevelopment: The genetic and microbiota link

V Ramírez, P González-Palacios, MA Baca… - Science of The Total …, 2022 - Elsevier
Current evidence highlights the importance of the genetic component in obesity and
neurodevelopmental disorders (attention-deficit hyperactivity disorder (ADHD), autism …