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Cell and animal models for studying hepatitis B virus infection and drug development
J Hu, YY Lin, PJ Chen, K Watashi, T Wakita - Gastroenterology, 2019 - Elsevier
Many cell culture and animal models have been used to study hepatitis B virus (HBV)
replication and its effects in the liver; these have facilitated development of strategies to …
replication and its effects in the liver; these have facilitated development of strategies to …
Host transcription factors in hepatitis B virus RNA synthesis
The hepatitis B virus (HBV) chronically infects over 250 million people worldwide and is one
of the leading causes of liver cancer and hepatocellular carcinoma. HBV persistence is due …
of the leading causes of liver cancer and hepatocellular carcinoma. HBV persistence is due …
The machinery for endocytosis of epidermal growth factor receptor coordinates the transport of incoming hepatitis B virus to the endosomal network
M Iwamoto, W Saso, K Nishioka, H Ohashi… - Journal of Biological …, 2020 - jbc.org
Sodium taurocholate cotransporting polypeptide (NTCP) is expressed at the surface of
human hepatocytes and functions as an entry receptor of hepatitis B virus (HBV). Recently …
human hepatocytes and functions as an entry receptor of hepatitis B virus (HBV). Recently …
Multifaceted interaction between hepatitis B virus infection and lipid metabolism in hepatocytes: a potential target of antiviral therapy for chronic hepatitis B
J Zhang, N Ling, Y Lei, M Peng, P Hu… - Frontiers in …, 2021 - frontiersin.org
Hepatitis B virus (HBV) is considered a “metabolic virus” and affects many hepatic metabolic
pathways. However, how HBV affects lipid metabolism in hepatocytes remains uncertain yet …
pathways. However, how HBV affects lipid metabolism in hepatocytes remains uncertain yet …
HBV cccDNA─ A culprit and stumbling block for the hepatitis B virus infection: its presence in hepatocytes perplexed the possible mission for a functional cure
Hepatitis B virus infection (HBV) is still a big health problem across the globe. It has been
linked to the development of liver cirrhosis and hepatocellular carcinoma and can trigger …
linked to the development of liver cirrhosis and hepatocellular carcinoma and can trigger …
Down-regulation of cell membrane localized NTCP expression in proliferating hepatocytes prevents hepatitis B virus infection
Y Yan, L Allweiss, D Yang, J Kang, J Wang… - Emerging microbes & …, 2019 - Taylor & Francis
Hepatocyte proliferation could result in the loss of covalently closed circular DNA (cccDNA)
and the emergence of cccDNA-cleared nascent hepatocytes, which appear refractory to …
and the emergence of cccDNA-cleared nascent hepatocytes, which appear refractory to …
Ferroptosis-related gene expression in the pathogenesis of preeclampsia
Y Ding, X Yang, X Han, M Shi, L Sun, M Liu… - Frontiers in …, 2022 - frontiersin.org
Background: Preeclampsia (PE) is one of the leading causes of maternal and fetal morbidity
and mortality worldwide. Placental oxidative stress has been identified as a major pathway …
and mortality worldwide. Placental oxidative stress has been identified as a major pathway …
What role for cellular metabolism in the control of hepatitis viruses?
O Diaz, PO Vidalain, C Ramière, V Lotteau… - Frontiers in …, 2022 - frontiersin.org
Hepatitis B, C and D viruses (HBV, HCV, HDV, respectively) specifically infect human
hepatocytes and often establish chronic viral infections of the liver, thus esca** antiviral …
hepatocytes and often establish chronic viral infections of the liver, thus esca** antiviral …
Farnesoid X receptor‐α is a proviral host factor for hepatitis B virus that is inhibited by ligands in vitro and in vivo
K Mouzannar, F Fusil, B Lacombe, A Ollivier… - The FASEB …, 2019 - Wiley Online Library
Hepatitis B virus (HBV) infection and bile acid (BA) metabolism are interdependent: infection
modifies the expression of the BA nuclear receptor farnesoid X receptor (FXR)‐α, and …
modifies the expression of the BA nuclear receptor farnesoid X receptor (FXR)‐α, and …
Low vitamin A levels are associated with liver-related mortality: A nationally representative cohort study
J Song, ZG Jiang - Hepatology Communications, 2023 - journals.lww.com
Methods: A total of 12,299 participants from the National Health and Nutrition Examination
Survey III (NHANES III) were analyzed to provide nationally representative estimates of the …
Survey III (NHANES III) were analyzed to provide nationally representative estimates of the …