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[HTML][HTML] Lipopolysaccharide-induced model of neuroinflammation: mechanisms of action, research application and future directions for its use
A Skrzypczak-Wiercioch, K Sałat - Molecules, 2022 - mdpi.com
Despite advances in antimicrobial and anti-inflammatory therapies, inflammation and its
consequences still remain a significant problem in medicine. Acute inflammatory responses …
consequences still remain a significant problem in medicine. Acute inflammatory responses …
The role of Toll-like receptors and neuroinflammation in Parkinson's disease
Background Parkinson's disease (PD) is the second most prevalent neurodegenerative
disorder, characterized by motor and non-motor symptoms, significantly affecting patients' …
disorder, characterized by motor and non-motor symptoms, significantly affecting patients' …
The lung microbiome regulates brain autoimmunity
L Hosang, RC Canals, FJ van der Flier, J Hollensteiner… - Nature, 2022 - nature.com
Lung infections and smoking are risk factors for multiple sclerosis, a T-cell-mediated
autoimmune disease of the central nervous system. In addition, the lung serves as a niche …
autoimmune disease of the central nervous system. In addition, the lung serves as a niche …
[HTML][HTML] Interplay of gut microbiota and oxidative stress: Perspective on neurodegeneration and neuroprotection
S Shandilya, S Kumar, NK Jha, KK Kesari… - Journal of Advanced …, 2022 - Elsevier
Background Recent research on the implications of gut microbiota on brain functions has
helped to gather important information on the relationship between them. Pathogenesis of …
helped to gather important information on the relationship between them. Pathogenesis of …
A fiber-deprived diet causes cognitive impairment and hippocampal microglia-mediated synaptic loss through the gut microbiota and metabolites
Background Cognitive impairment, an increasing mental health issue, is a core feature of the
aging brain and neurodegenerative diseases. Industrialized nations especially, have …
aging brain and neurodegenerative diseases. Industrialized nations especially, have …
Gut microbial molecules in behavioural and neurodegenerative conditions
BD Needham, R Kaddurah-Daouk… - Nature Reviews …, 2020 - nature.com
Mounting evidence suggests that the gut microbiome impacts brain development and
function. Gut–brain connections may be mediated by an assortment of microbial molecules …
function. Gut–brain connections may be mediated by an assortment of microbial molecules …
The endotoxin hypothesis of neurodegeneration
GC Brown - Journal of neuroinflammation, 2019 - Springer
The endotoxin hypothesis of neurodegeneration is the hypothesis that endotoxin causes or
contributes to neurodegeneration. Endotoxin is a lipopolysaccharide (LPS), constituting …
contributes to neurodegeneration. Endotoxin is a lipopolysaccharide (LPS), constituting …
Short-chain fatty acids and lipopolysaccharide as mediators between gut dysbiosis and amyloid pathology in Alzheimer's disease
M Marizzoni, A Cattaneo, P Mirabelli… - Journal of …, 2020 - journals.sagepub.com
Background: Metagenomic data support an association between certain bacterial strains
and Alzheimer's disease (AD), but their functional dynamics remain elusive. Objective: To …
and Alzheimer's disease (AD), but their functional dynamics remain elusive. Objective: To …
Gut–brain axis: role of gut microbiota on neurological disorders and how probiotics/prebiotics beneficially modulate microbial and immune pathways to improve brain …
K Suganya, BS Koo - International journal of molecular sciences, 2020 - mdpi.com
The gut microbiome acts as an integral part of the gastrointestinal tract (GIT) that has the
largest and vulnerable surface with desirable features to observe foods, nutrients, and …
largest and vulnerable surface with desirable features to observe foods, nutrients, and …
The endotoxin hypothesis of Parkinson's disease
The endotoxin hypothesis of Parkinson's disease (PD) is the idea that lipopolysaccharide
(LPS) endotoxins contribute to the pathogenesis of this disorder. LPS endotoxins are found …
(LPS) endotoxins contribute to the pathogenesis of this disorder. LPS endotoxins are found …