Highlights•Next generation sequencing technologies have enabled large-scale genome
analyses.•Pan-genome analyses provide a framework for predicting and modeling genomic …

With the advance of sequencing technologies, the landscape of genomic analysis has been
transformed, by moving from single strain to species (or even higher taxa)-wide genomic …

Abstract In 2004, the SEED (http://pubseed. theseed. org/) was created to provide consistent
and accurate genome annotations across thousands of genomes and as a platform for …

Pan‐genomics is one of the most powerful means to study genomic variation and obtain a
sketch of genes within a defined clade of species. Though there are a lot of computational …

Since the proposal for pangenomic study, there have been a dozen software tools actively in
use for pangenomic analysis. By the end of 2014, Panseq and the pan-genomes analysis …

An astronomical increase in microbial genome data in recent years has led to strong
demand for bioinformatic tools for pan-genome analysis within and across species. Here, we …

Bacteriophages are the most prevalent biological entities in the biosphere. However,
limitations in both medical relevance and sequencing technologies have led to a systematic …

Advances in sequencing technologies and bioinformatics tools have fueled a renewed
interest in whole genome sequencing efforts in many organisms. The growing availability of …

The Bifidobacterium longum 5 1A strain of isolated from feces of a healthy child, has
demonstrated probiotic properties by in vivo and in vitro studies, which may be assigned to …

Computational pan-genome analysis has emerged from the rapid increase of available
genome sequencing data. Starting from a microbial pan-genome, the concept has spread to …