Stem cells perform many different functions, each of which requires specific metabolic
adaptations. Over the past decades, studies of pluripotent and tissue stem cells have …

Gastrulation is a key milestone in the development of an organism. It is a period of cell
proliferation and coordinated cellular rearrangement, that creates an outline of the body …

The prevailing dogma for morphological patterning in develo** organisms argues that the
combined inputs of transcription factor networks and signalling morphogens alone generate …

Numerous cellular and molecular processes during embryonic development prompt the
fundamental question of how their tempos are coordinated and whether a common global …

Mammalian stem-cell-based models of embryo development (stembryos) hold great promise
in basic and applied research. However, considerable phenotypic variation despite identical …

Organoids and stem-cell-based embryo models (SEMs) are imperfect organ or embryo
representations that explore a much larger space of possible forms, or morphospace …

Patterning and growth are fundamental features of embryonic development that must be
tightly coordinated. To understand how metabolism impacts early mesoderm development …

The question of how metabolism impacts development is seeing a renaissance [,]. How
metabolism exerts instructive signaling functions is one of the central issues that need to be …

The field of developmental metabolism is experiencing a technological revolution that is
opening entirely new fields of inquiry. Advances in metabolomics, small-molecule sensors …

Development consists of a highly ordered suite of steps and transitions, like choreography.
Although these sequences are often evolutionarily conserved, they can display species …