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Gut microbiota in colorectal cancer development and therapy
Colorectal cancer (CRC) is one of the commonest cancers globally. A unique aspect of CRC
is its intimate association with the gut microbiota, which forms an essential part of the tumour …
is its intimate association with the gut microbiota, which forms an essential part of the tumour …
Increasing incidence of early-onset colorectal cancer
FA Sinicrope - New England Journal of Medicine, 2022 - Mass Medical Soc
Early-Onset Colorectal Cancer Early-onset disease (at< 50 years of age) accounts for 10%
of colorectal cancer cases, and the incidence is increasing, particularly in high-income …
of colorectal cancer cases, and the incidence is increasing, particularly in high-income …
[HTML][HTML] Tumor-resident intracellular microbiota promotes metastatic colonization in breast cancer
A Fu, B Yao, T Dong, Y Chen, J Yao, Y Liu, H Li, H Bai… - Cell, 2022 - cell.com
Tumor-resident intracellular microbiota is an emerging tumor component that has been
documented for a variety of cancer types with unclear biological functions. Here, we …
documented for a variety of cancer types with unclear biological functions. Here, we …
Role of the gut microbiota and its metabolites in tumorigenesis or development of colorectal cancer
R Qu, Y Zhang, Y Ma, X Zhou, L Sun, C Jiang… - Advanced …, 2023 - Wiley Online Library
Colorectal cancer (CRC) is the most common cancer of the digestive system with high
mortality and morbidity rates. Gut microbiota is found in the intestines, especially the …
mortality and morbidity rates. Gut microbiota is found in the intestines, especially the …
Understanding the role of the gut microbiome in gastrointestinal cancer: A review
Gastrointestinal cancer represents one of the most diagnosed types of cancer. Cancer is a
genetic and multifactorial disease, influenced by the host and environmental factors. It has …
genetic and multifactorial disease, influenced by the host and environmental factors. It has …
The microbiome and human cancer
BACKGROUND Historical accounts linking cancer and microbes date as early as four
millennia ago. After establishment of the germ theory of infectious diseases, clinical research …
millennia ago. After establishment of the germ theory of infectious diseases, clinical research …
The inflammatory pathogenesis of colorectal cancer
M Schmitt, FR Greten - Nature Reviews Immunology, 2021 - nature.com
The mutational landscape of colorectal cancer (CRC) does not enable predictions to be
made about the survival of patients or their response to therapy. Instead, studying the …
made about the survival of patients or their response to therapy. Instead, studying the …
Global burden of colorectal cancer: emerging trends, risk factors and prevention strategies
NN Keum, E Giovannucci - Nature reviews Gastroenterology & …, 2019 - nature.com
Globally, colorectal cancer (CRC) is the third most commonly diagnosed malignancy and the
second leading cause of cancer death. Arising through three major pathways, including …
second leading cause of cancer death. Arising through three major pathways, including …
Gut microbiota in colorectal cancer: mechanisms of action and clinical applications
Colorectal cancer (CRC) accounts for about 10% of all new cancer cases globally. Located
at close proximity to the colorectal epithelium, the gut microbiota comprises a large …
at close proximity to the colorectal epithelium, the gut microbiota comprises a large …
Signaling pathways involved in colorectal cancer: Pathogenesis and targeted therapy
Q Li, S Geng, H Luo, W Wang, YQ Mo, Q Luo… - … and Targeted Therapy, 2024 - nature.com
Colorectal cancer (CRC) remains one of the leading causes of cancer-related mortality
worldwide. Its complexity is influenced by various signal transduction networks that govern …
worldwide. Its complexity is influenced by various signal transduction networks that govern …