Near-infrared metal agents assisting precision medicine: from strategic design to bioimaging and therapeutic applications

C Li, Y Pang, Y Xu, M Lu, L Tu, Q Li… - Chemical Society …, 2023‏ - pubs.rsc.org
Metal agents have made incredible strides in preclinical research and clinical applications in
recent years, but their short emission/absorption wavelengths continue to be a barrier to …

BODIPY as a Multifunctional Theranostic Reagent in Biomedicine: Self‐Assembly, Properties, and Applications

HB Cheng, X Cao, S Zhang, K Zhang… - Advanced …, 2023‏ - Wiley Online Library
The use of boron dipyrromethene (BODIPY) in biomedicine is reviewed. To open, its
synthesis and regulatory strategies are summarized, and inspiring cutting‐edge work in post …

Nanoparticle‐based photothermal therapy for breast cancer noninvasive treatment

Y **ong, Y Rao, J Hu, Z Luo, C Chen - Advanced materials, 2023‏ - Wiley Online Library
Rapid advancements in materials science and nanotechnology, intertwined with oncology,
have positioned photothermal therapy (PTT) as a promising noninvasive treatment strategy …

Rational design in photopharmacology with molecular photoswitches

P Kobauri, FJ Dekker, W Szymanski… - Angewandte Chemie …, 2023‏ - Wiley Online Library
Photopharmacology is an attractive approach for achieving targeted drug action with the use
of light. In photopharmacology, molecular photoswitches are introduced into the structure of …

Photocatalytic superoxide radical generator that induces pyroptosis in cancer cells

L Yu, Y Xu, Z Pu, H Kang, M Li… - Journal of the …, 2022‏ - ACS Publications
Pyroptosis, a newly characterized form of immunogenic cell death, is attracting increasing
attention as a promising approach to cancer immunotherapy. However, biocompatible …

Bioorthogonal chemistry for prodrug activation in vivo

Q Fu, S Shen, P Sun, Z Gu, Y Bai, X Wang… - Chemical Society …, 2023‏ - pubs.rsc.org
Prodrugs have emerged as a major strategy for addressing clinical challenges by improving
drug pharmacokinetics, reducing toxicity, and enhancing treatment efficacy. The emergence …

meso-Methyl BODIPY Photocages: Mechanisms, Photochemical Properties, and Applications

P Shrestha, D Kand, R Weinstain… - Journal of the American …, 2023‏ - ACS Publications
meso-methyl BODIPY photocages have recently emerged as an exciting new class of
photoremovable protecting groups (PPGs) that release leaving groups upon absorption of …

Visible-light and near-infrared fluorescence and surface-enhanced Raman scattering point-of-care sensing and bio-imaging: a review

Y Hang, J Boryczka, N Wu - Chemical Society Reviews, 2022‏ - pubs.rsc.org
This review article deals with the concepts, principles and applications of visible-light and
near-infrared (NIR) fluorescence and surface-enhanced Raman scattering (SERS) in in vitro …

Radiotherapy activates picolinium prodrugs in tumours

Q Fu, Z Gu, S Shen, Y Bai, X Wang, M Xu, P Sun… - Nature Chemistry, 2024‏ - nature.com
Radiotherapy-induced prodrug activation provides an ideal solution to reduce the systemic
toxicity of chemotherapy in cancer therapy, but the scope of the radiation-activated …

Photosensitive and conductive hydrogel induced innerved bone regeneration for infected bone defect repair

X **g, C Xu, W Su, Q Ding, B Ye, Y Su… - Advanced …, 2023‏ - Wiley Online Library
Repairing infected bone defects is a challenge in the field of orthopedics because of the
limited self‐healing capacity of bone tissue and the susceptibility of refractory materials to …