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The neurovasculome: key roles in brain health and cognitive impairment: a scientific statement from the American Heart Association/American Stroke Association
C Iadecola, EE Smith, J Anrather, C Gu, A Mishra… - Stroke, 2023 - ahajournals.org
Background: Preservation of brain health has emerged as a leading public health priority for
the aging world population. Advances in neurovascular biology have revealed an intricate …
the aging world population. Advances in neurovascular biology have revealed an intricate …
Neuroinflammation in Alzheimer's disease: insights from peripheral immune cells
Q Zhang, G Yang, Y Luo, L Jiang, H Chi, G Tian - Immunity & Ageing, 2024 - Springer
Alzheimer's disease (AD) is a serious brain disorder characterized by the presence of beta-
amyloid plaques, tau pathology, inflammation, neurodegeneration, and cerebrovascular …
amyloid plaques, tau pathology, inflammation, neurodegeneration, and cerebrovascular …
[HTML][HTML] Experimental and clinical biomarkers for progressive evaluation of neuropathology and therapeutic interventions for acute and chronic neurological disorders
DS Reddy, HN Abeygunaratne - International Journal of Molecular …, 2022 - mdpi.com
This article describes commonly used experimental and clinical biomarkers of neuronal
injury and neurodegeneration for the evaluation of neuropathology and monitoring of …
injury and neurodegeneration for the evaluation of neuropathology and monitoring of …
Modeling the neuroimmune system in Alzheimer's and Parkinson's diseases
W Balestri, R Sharma, VA da Silva, BC Bobotis… - Journal of …, 2024 - Springer
Parkinson's disease (PD) and Alzheimer's disease (AD) are neurodegenerative disorders
caused by the interaction of genetic, environmental, and familial factors. These diseases …
caused by the interaction of genetic, environmental, and familial factors. These diseases …
[HTML][HTML] Abnormal amyloid beta metabolism in systemic abnormalities and Alzheimer's pathology: Insights and therapeutic approaches from periphery
Alzheimer's disease (AD) is an age-associated, multifactorial neurodegenerative disorder
that is incurable. Despite recent success in treatments that partially improve symptomatic …
that is incurable. Despite recent success in treatments that partially improve symptomatic …
Dementia, infections and vaccines: 30 years of controversy
F Ecarnot, V Boccardi, A Calcagno… - Aging Clinical and …, 2023 - Springer
This paper reports the proceedings of a virtual meeting convened by the European
Interdisciplinary Council on Ageing (EICA), to discuss the involvement of infectious disorders …
Interdisciplinary Council on Ageing (EICA), to discuss the involvement of infectious disorders …
Infiltration of immune cells to the brain and its relation to the pathogenesis of Alzheimer's and Parkinson's diseases
C Netzahualcoyotzi, JJ Santillán‐Cigales… - Journal of …, 2024 - Wiley Online Library
The neurovascular unit, composed of vascular endothelium, vascular smooth muscle,
extracellular matrix components, pericytes, astrocytes, microglia, and neurons, allows the …
extracellular matrix components, pericytes, astrocytes, microglia, and neurons, allows the …
ABCA7-Associated Clinical Features and Molecular Mechanisms in Alzheimer's Disease
X Qian, S Chen, X Liu, H Tang - Molecular Neurobiology, 2023 - Springer
Alzheimer's disease (AD) is the most common type of neurodegenerative disease and its
pathogenesis is still unclear. Genetic factors are thought to account for a large proportion of …
pathogenesis is still unclear. Genetic factors are thought to account for a large proportion of …
Ad-derived bone marrow transplant induces proinflammatory immune peripheral mechanisms accompanied by decreased neuroplasticity and reduced gut …
R Iban-Arias, EJ Yang, E Griggs, ASD Portela… - Brain, Behavior, and …, 2024 - Elsevier
Immune system dysfunction is increasingly recognized as a significant feature that
contributes to Alzheimer's disease (AD) pathogenesis, reflected by alterations in central and …
contributes to Alzheimer's disease (AD) pathogenesis, reflected by alterations in central and …
Monocyte regulation by gut microbial signals
P Kolypetri, HL Weiner - Trends in microbiology, 2023 - cell.com
Monocytes are innate immune cells that sense environmental changes and participate in the
immunoregulation of autoimmune, neurologic, cardiovascular, and metabolic diseases as …
immunoregulation of autoimmune, neurologic, cardiovascular, and metabolic diseases as …