As the home of cellular genetic information, the nucleus has a critical role in determining cell
fate and function in response to various signals and stimuli. In addition to biochemical …

Cells and tissues can sense and react to the modifications of the physico-chemical
properties of the extracellular environment (ECM) through integrin-based adhesion sites and …

Progress in the field of nanoparticles has enabled the rapid development of multiple
products and technologies; however, some nanoparticles can pose both a threat to the …

Nuclear lamins are type‐V intermediate filaments that are involved in many nuclear
processes. In mammals, A‐and B‐type lamins assemble into separate physical meshwork …

Geometrical cues provided by the intrinsic architecture of tissues and implanted biomaterials
have a high relevance in controlling cellular behavior. Knowledge of how cells sense and …

While various cell responses on material surfaces have been examined, relatively few
reports are focused on significant self-deformation of cell nuclei and corresponding …

Cells respond to the mechanical signals from their surroundings and integrate
physiochemical signals to initiate intricate mechanochemical processes. While many studies …

Our previous studies of PAWS1 (protein associated with SMAD1; also known as FAM83G)
have suggested that this molecule has roles beyond BMP signalling. To investigate these …

Endothelial cell (EC) dysfunction contributes to atherosclerosis, which is associated with
arterial stiffening and fibronectin (FN) deposition, by ECs and smooth muscle cells (SMCs) …

The success of scaffold-guided tissue regeneration largely depends on the formation of new
tissue in a native-like organization in order to ensure proper tissue function. A well …