Neuroinflammation and microglial activation in Alzheimer disease: where do we go from here?
Alzheimer disease (AD) is the most common form of neurodegenerative disease, estimated
to contribute 60–70% of all cases of dementia worldwide. According to the prevailing …
to contribute 60–70% of all cases of dementia worldwide. According to the prevailing …
The sirtuin family in health and disease
QJ Wu, TN Zhang, HH Chen, XF Yu, JL Lv… - … and Targeted Therapy, 2022 - nature.com
Sirtuins (SIRTs) are nicotine adenine dinucleotide (+)-dependent histone deacetylases
regulating critical signaling pathways in prokaryotes and eukaryotes, and are involved in …
regulating critical signaling pathways in prokaryotes and eukaryotes, and are involved in …
[HTML][HTML] Resveratrol (RV): A pharmacological review and call for further research
Resveratrol (RV) is a well-known polyphenolic compound in various plants, including grape,
peanut, and berry fruits, which is quite famous for its association with several health benefits …
peanut, and berry fruits, which is quite famous for its association with several health benefits …
Nutrition, physical activity, and other lifestyle factors in the prevention of cognitive decline and dementia
LJ Dominguez, N Veronese, L Vernuccio, G Catanese… - Nutrients, 2021 - mdpi.com
Multiple factors combined are currently recognized as contributors to cognitive decline. The
main independent risk factor for cognitive impairment and dementia is advanced age …
main independent risk factor for cognitive impairment and dementia is advanced age …
Astrocytic and microglial cells as the modulators of neuroinflammation in Alzheimer's disease
D Singh - Journal of neuroinflammation, 2022 - Springer
Neuroinflammation is instigated by the misfiring of immune cells in the central nervous
system (CNS) involving microglia and astrocytes as key cell-types. Neuroinflammation is a …
system (CNS) involving microglia and astrocytes as key cell-types. Neuroinflammation is a …
The therapeutic potential of resveratrol: a review of clinical trials
AY Berman, RA Motechin, MY Wiesenfeld… - NPJ precision …, 2017 - nature.com
Resveratrol is a nutraceutical with several therapeutic effects. It has been shown to mimic
effects of caloric restriction, exert anti-inflammatory and anti-oxidative effects, and affect the …
effects of caloric restriction, exert anti-inflammatory and anti-oxidative effects, and affect the …
Healthy effects of plant polyphenols: molecular mechanisms
The increasing extension in life expectancy of human beings in developed countries is
accompanied by a progressively greater rate of degenerative diseases associated with …
accompanied by a progressively greater rate of degenerative diseases associated with …
Development of multifunctional molecules as potential therapeutic candidates for Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis in the …
Neurodegenerative diseases pose a substantial socioeconomic burden on society.
Unfortunately, the aging world population and lack of effective cures foreshadow a negative …
Unfortunately, the aging world population and lack of effective cures foreshadow a negative …
Health benefits of resveratrol: Evidence from clinical studies
AP Singh, R Singh, SS Verma, V Rai… - Medicinal research …, 2019 - Wiley Online Library
Resveratrol is a polyphenolic nutraceutical that exhibits pleiotropic activities in human
subjects. The efficacy, safety, and pharmacokinetics of resveratrol have been documented in …
subjects. The efficacy, safety, and pharmacokinetics of resveratrol have been documented in …
Neuroinflammation in Alzheimer's disease
IG Onyango, GV Jauregui, M Čarná, JP Bennett Jr… - Biomedicines, 2021 - mdpi.com
Alzheimer's disease (AD) is a neurodegenerative disease associated with human aging.
Ten percent of individuals over 65 years have AD and its prevalence continues to rise with …
Ten percent of individuals over 65 years have AD and its prevalence continues to rise with …