The mechanistic underpinnings of autism remain a subject of debate and controversy. Why
do individuals with autism share an overlap** set of atypical behaviors and symptoms …

Stress-related psychiatric disorders including depression involve complex cellular and
molecular changes in the brain, and GABAergic signaling dysfunction is increasingly …

Exposure of an organism to chronic psychosocial stress may affect brain-derived
neurotrophic factor (BDNF) expression that has been implicated in the etiology of psychiatric …

Cholecystokinin (CCK)-and parvalbumin (PV)-expressing neurons constitute the two major
populations of perisomatic GABAergic neurons in the cortex and the hippocampus. As CCK …

Depression is an increasingly common but extremely serve mood disorder that remains
poorly understood and inadequately treated. Fast-spiking parvalbumin-positive interneurons …

We have previously reported that mild TBI created by focal left-side cranial blast in mice
produces widespread axonal injury, microglial activation, and a variety of functional deficits …

Studies in humans and rodents suggest a critical role for the hippocampal formation in
cognition and emotion, but also in the adaptation to stressful events. Successful stress …

Azadiradione is a small bioactive limonoid found in the seed of Azadirachta Indica, an Indian
medicinal plant commonly known as Neem. Recently, it has been shown to ameliorate the …

The hippocampus is a brain structure involved in the regulation of hypothalamic-pituitary-
adrenal (HPA) axis and stress response. It plays an important role in the formation of …

Alzheimer's disease (AD) is the most common cause of dementia. In addition to cognitive
impairments, deficits in non-cognitive behaviors are also common neurological sequelae in …