Exploring emergent properties in enzymatic reaction networks: design and control of dynamic functional systems

S Ghosh, MG Baltussen, NM Ivanov, R Haije… - Chemical …, 2024 - ACS Publications
The intricate and complex features of enzymatic reaction networks (ERNs) play a key role in
the emergence and sustenance of life. Constructing such networks in vitro enables stepwise …

Optimizing the standardized assays for determining the catalytic activity and kinetics of peroxidase-like nanozymes

JJ Zheng, F Zhu, N Song, F Deng, Q Chen, C Chen… - Nature …, 2024 - nature.com
Nanozymes are nanomaterials with enzyme-like catalytic properties. They are attractive
reagents because they do not have the same limitations of natural enzymes (eg, high cost …

Synthetic biomarkers: a twenty-first century path to early cancer detection

GA Kwong, S Ghosh, L Gamboa, C Patriotis… - Nature Reviews …, 2021 - nature.com
Detection of cancer at an early stage when it is still localized improves patient response to
medical interventions for most cancer types. The success of screening tools such as cervical …

Cold atmospheric plasma delivery for biomedical applications

Z Chen, G Chen, R Obenchain, R Zhang, F Bai, T Fang… - Materials Today, 2022 - Elsevier
As the fourth state of matter, plasma's unique properties and interactions with other states of
matter offer many promising opportunities for investigation and discovery. In particular, cold …

Smart data processing for energy harvesting systems using artificial intelligence

S Divya, S Panda, S Hajra, R Jeyaraj, A Paul, SH Park… - Nano Energy, 2023 - Elsevier
Recent substantial advancements in computational techniques, particularly in artificial
intelligence (AI) and machine learning (ML), have raised the demand for smart self-powered …

[HTML][HTML] Microbial L-asparaginase for application in acrylamide mitigation from food: Current research status and future perspectives

R Jia, X Wan, X Geng, D Xue, Z **e, C Chen - Microorganisms, 2021 - mdpi.com
L-asparaginase (EC 3.5. 1.1) hydrolyzes L-asparagine to L-aspartic acid and ammonia,
which has been widely applied in the pharmaceutical and food industries. Microbes have …

High-efficiency silicon heterojunction solar cells: materials, devices and applications

Y Liu, Y Li, Y Wu, G Yang, L Mazzarella… - Materials Science and …, 2020 - Elsevier
Photovoltaic (PV) technology offers an economic and sustainable solution to the challenge
of increasing energy demand in times of global warming. The world PV market is currently …

Covalent proximity scanning of a distal cysteine to target PI3Kα

C Borsari, E Keles, JA McPhail… - Journal of the …, 2022 - ACS Publications
Covalent protein kinase inhibitors exploit currently noncatalytic cysteines in the adenosine
5′-triphosphate (ATP)-binding site via electrophiles directly appended to a reversible …

L-asparaginase production review: bioprocess design and biochemical characteristics

D Castro, ASC Marques, MR Almeida… - Applied microbiology …, 2021 - Springer
In the past decades, the production of biopharmaceuticals has gained high interest due to its
great sensitivity, specificity, and lower risk of negative effects to patients. Biopharmaceuticals …

Identifiability analysis for stochastic differential equation models in systems biology

AP Browning, DJ Warne, K Burrage… - Journal of the …, 2020 - royalsocietypublishing.org
Mathematical models are routinely calibrated to experimental data, with goals ranging from
building predictive models to quantifying parameters that cannot be measured. Whether or …