Prenatal environmental risk factors for autism spectrum disorder and their potential mechanisms
Autism spectrum disorder (ASD) is a neurodevelopmental disorder that is globally
increasing in prevalence. The rise of ASD can be partially attributed to diagnostic expansion …
increasing in prevalence. The rise of ASD can be partially attributed to diagnostic expansion …
[HTML][HTML] Sex differences in antioxidant defence and the regulation of redox homeostasis in physiology and pathology
Reactive oxygen species (ROS) is a term that defines a group of unstable compounds
derived from exogenous sources or endogenous metabolism. Under physiological …
derived from exogenous sources or endogenous metabolism. Under physiological …
Multiple classification of brain MRI autism spectrum disorder by age and gender using deep learning
The fact that the rapid and definitive diagnosis of autism cannot be made today and that
autism cannot be treated provides an impetus to look into novel technological solutions. To …
autism cannot be treated provides an impetus to look into novel technological solutions. To …
Differences in regional brain structure in toddlers with autism are related to future language outcomes
Abstract Language and social symptoms improve with age in some autistic toddlers, but not
in others, and such outcome differences are not clearly predictable from clinical scores …
in others, and such outcome differences are not clearly predictable from clinical scores …
Sex-specific microglia state in the Neuroligin-4 knock-out mouse model of autism spectrum disorder
Abstract Neuroligin-4 (NLGN4) loss-of-function mutations are associated with monogenic
heritable autism spectrum disorder (ASD) and cause alterations in both synaptic and …
heritable autism spectrum disorder (ASD) and cause alterations in both synaptic and …
Embryonic exposure to environmental factors drives transmitter switching in the neonatal mouse cortex causing autistic-like adult behavior
Autism spectrum disorders (ASD) can be caused by environmental factors. These factors act
early in the development of the nervous system and induce stereotyped repetitive behaviors …
early in the development of the nervous system and induce stereotyped repetitive behaviors …
Maternal immune activation induced by prenatal lipopolysaccharide exposure leads to long-lasting autistic-like social, cognitive and immune alterations in male Wistar …
E Carbone, V Buzzelli, A Manduca, S Leone… - International journal of …, 2023 - mdpi.com
Several studies have supported the association between maternal immune activation (MIA)
caused by exposure to pathogens or inflammation during critical periods of gestation and an …
caused by exposure to pathogens or inflammation during critical periods of gestation and an …
Chromosome X-wide common variant association study in autism spectrum disorder
Autism spectrum disorder (ASD) displays a notable male bias in prevalence. Research into
rare (< 0.1) genetic variants on the X chromosome has implicated over 20 genes in ASD …
rare (< 0.1) genetic variants on the X chromosome has implicated over 20 genes in ASD …
Medial prefrontal cortex circuitry and social behaviour in autism
DH Mediane, S Basu, EN Cahill, PG Anastasiades - Neuropharmacology, 2024 - Elsevier
Autism spectrum disorder (ASD) has proven to be highly enigmatic due to the diversity of its
underlying genetic causes and the huge variability in symptom presentation. Uncovering …
underlying genetic causes and the huge variability in symptom presentation. Uncovering …
Mutations associated with autism lead to similar synaptic and behavioral alterations in both sexes of male and female mouse brain
MK Tripathi, SK Ojha, M Kartawy, I Khaliulin… - Scientific Reports, 2024 - nature.com
Autism spectrum disorder (ASD) is a neurodevelopmental disorder based on synaptic
abnormalities. The estimated prevalence rate of male individuals diagnosed with ASD …
abnormalities. The estimated prevalence rate of male individuals diagnosed with ASD …