[HTML][HTML] Humoral theory of transplantation

PI Terasaki - American Journal of Transplantation, 2003 - Elsevier
According to the humoral theory of transplantation, antibodies cause allograft rejection.
Publications are cited showing that antibodies:(1) cause hyperacute kidney rejection,(2) …

Interactions between the recipient immune system and the left ventricular assist device surface: immunological and clinical implications

S Itescu, R John - The Annals of thoracic surgery, 2003 - Elsevier
The unquestionable clinical success of left ventricular assist device (LVAD) implantation
has, nevertheless, been accompanied by complications arising from interactions between …

Evaluation of intravenous immunoglobulin as an agent to lower allosensitization and improve transplantation in highly sensitized adult patients with end-stage renal …

SC Jordan, D Tyan, D Stablein… - Journal of the …, 2004 - journals.lww.com
Reported are the reduction of anti-HLA antibody levels and improvement of transplant rates
by intravenous immunoglobulin (IVIG) in a randomized, double-blind, placebo-controlled …

[HTML][HTML] Desensitization and subsequent kidney transplantation of patients using intravenous immunoglobulins (IVIg)

D Glotz, C Antoine, P Julia… - American Journal of …, 2002 - Elsevier
Transplantation of patients possessing antibodies against allo‐HLA antigens can be
delayed for years. We have shown that administration of intravenous immunoglobulins (IVIg) …

Posttransplant therapy using high-dose human immunoglobulin (intravenous gammaglobulin) to control acute humoral rejection in renal and cardiac allograft …

SC Jordan, AW Quartel, LSC Czer, D Admon… - …, 1998 - journals.lww.com
Background. Intravenous gammaglobulin (IVIG) contains anti-idiotypic antibodies that are
potent inhibitors of HLA-specific alloantibodies in vitro and in vivo. In addition, highly HLA …

Intravenous immune globulin in the therapy of peripartum cardiomyopathy

B Bozkurt, FS Villaneuva, R Holubkov… - Journal of the American …, 1999 - jacc.org
OBJECTIVES We sought to evaluate the effect of therapy with intravenous immune globulin
on recovery of left ventricular function in women presenting with peripartum cardiomyopathy …

Intravenous immune globulin treatment inhibits crossmatch positivity and allows for successful transplantation of incompatible organs in living-donor and cadaver …

SC Jordan, A Vo, S Bunnapradist, M Toyoda… - …, 2003 - journals.lww.com
Background. Sensitization to human leukocyte antigens (HLA) is a significant barrier to
transplantation. Currently, no proven therapy exists to improve access to transplantation for …

Intravenous immunoglobulin reduces anti-HLA alloreactivity and shortens waiting time to cardiac transplantation in highly sensitized left ventricular assist device …

R John, K Lietz, E Burke, J Ankersmit, D Mancini… - Circulation, 1999 - ahajournals.org
Background—Recipients of left ventricular assist devices (LVADs) develop prominent B-cell
hyperreactivity. We investigated the influence of anti-HLA antibodies on waiting time to …

Plasmapheresis with intravenous immunoglobulin G is effective in patients with elevated panel reactive antibody prior to cardiac transplantation

BA Pisani, GM Mullen, K Malinowska… - The Journal of heart and …, 1999 - Elsevier
BACKGROUND: Patients with a PRA> 10% are considered to be at greater risk for the
development of not only acute cellular and humoral rejection but also increased mortality …

Preformed IgG antibodies against major histocompatibility complex class II antigens are major risk factors for high-grade cellular rejection in recipients of heart …

S Itescu, TC Tung, EM Burke, A Weinberg, N Moazami… - Circulation, 1998 - ahajournals.org
Background—Preformed anti-HLA antibodies reacting specifically with donor lymphocytes
have been associated with acute vascular rejection and early cardiac allograft failure …