The optimism of the early period of antimicrobial discovery has been tempered by the
emergence of bacterial strains with resistance to these therapeutics. Today, clinically …

History of mankind is regarded as struggle against infectious diseases. Rather than
observing the withering away of bacterial diseases, antibiotic resistance has emerged as a …

Acinetobacter baumannii (A. baumannii) is undoubtedly one of the most successful
pathogens in the modern healthcare system. With invasive procedures, antibiotic use and …

As recently indiscriminate abuse of existing antibiotics in both clinical and veterinary
treatment leads to proliferation of antibiotic resistance in microbes and poses a dilemma for …

The basic mechanisms of antibacterial resistance are well known, but critical new aspects
continue to be discovered. Recently discovered factors with major implications for the …

INTEGRALL is a freely available, text-based search system developed with the aim of
collecting and organizing information on integrons in a single database. The current release …

Integrons are genetic elements composed of a gene encoding an integrase, gene cassettes
and an integration site for the gene cassettes (att). The integrase excises and integrates the …

ABSTRACT From January 2001 to December 2002, 587 strains of gram-negative bacterial
isolates demonstrating resistance to ceftazidime and a combination of sulbactam and …

Antibiotic resistance development and pathogen cross-dissemination are both considered
essential risks to human health on a worldwide scale. Antimicrobial resistance genes …

Antimicrobial resistant strains of bacteria are an increasing threat to animal and human
health. Resistance mechanisms to circumvent the toxic action of antimicrobials have been …