Purpose Loneliness is increasingly recognised as the next critical public health issue. A
plausible reason for this concern may be related to emerging societal trends affecting the …

Aim: The etiology of hypertension is various and complex, involving both genetic and
behavioral factors. The relationship between psychosocial stress and hypertension has …

The detrimental effects of stress on human health are being increasingly recognized. There
is a critical need for the establishment of a biomarker that accurately measures its intensity …

Diabetes and hypertension frequently occur together. There is substantial overlap between
diabetes and hypertension in etiology and disease mechanisms. Obesity, inflammation …

The London physician and neuroanatomist Thomas Willis in the 17th century correctly
attributed the source of emotions to the brain, not the heart as believed in antiquity …

Cumulative acute psychosocial stress is thought to promote the development of a range of
disorders which suggests that biomarkers for the physiological response may become …

Endothelial dysfunction is one of the earliest manifestations of atherosclerosis, contributing
to its development and progression. Mental stress induces endothelial dysfunction through …

There is a strong association between late-life depression, cognitive impairment,
cerebrovascular disease, and poor cognitive outcomes, including progressive dementia …

Translational medicine is concerned with the translation of research discoveries into clinical
applications for the prevention, diagnosis, and treatment of human diseases. Here we briefly …

The world wide prevalence of obesity and the metabolic syndrome is escalating. Contrary to
earlier experimental evidence, human obesity is characterised by sympathetic nervous …