Among the prokaryotic genomic islands (GIs) involved in horizontal gene transfer (HGT) are
the classical pathogenicity islands, including the integrative and conjugative elements …

For many,“DNA mimic protein”(DMP) remains an unfamiliar term. The key feature of these
proteins is their DNA‐like shape and charge distribution, and they affect the activity of DNA …

The dUTPase is a key DNA repair enzyme in Mycobacterium tuberculosis, and it may serve
as a novel promising anti-tuberculosis target. Stl repressor from Staphylococcus aureus was …

Arginine finger is a highly conserved and essential residue in many GTPase and AAA+
ATPase enzymes that completes the active site from a distinct protomer, forming contacts …

Fine-tuned regulation of the cellular nucleotide pools is indispensable for faithful replication
of Deoxyribonucleic Acid (DNA). The genetic information is also safeguarded by DNA …

Targeting conserved and essential processes is a successful strategy to combat enemies.
Remarkably, the clinically important Staphylococcus aureus pathogenicity islands (SaPIs) …

Abstract Human deoxyuridine 5′-triphosphate nucleotidohydrolase (dUTPase), essential
for DNA integrity, acts as a survival factor for tumor cells and is a target for cancer …

Abstract dUTPase superfamily enzymes generate dUMP, the obligate precursor for de novo
dTTP biosynthesis, from either dUTP (monofunctional dUTPase, Dut) or dCTP (bifunctional …

It has been demonstrated recently that knockout of the dUTPase enzyme leads to early
embryonic lethality in mice. However, to explore the physiological processes arising upon …

Background Bacillus strains producing highly resistant spores have been isolated from
cleanrooms and space craft assembly facilities. Organisms that can survive such conditions …