Effects of ionizing radiation on biological molecules—mechanisms of damage and emerging methods of detection

JA Reisz, N Bansal, J Qian, W Zhao… - Antioxidants & redox …, 2014 - liebertpub.com
Significance: The detrimental effects of ionizing radiation (IR) involve a highly orchestrated
series of events that are amplified by endogenous signaling and culminating in oxidative …

Protein carbonylation as a major hallmark of oxidative damage: update of analytical strategies

M Fedorova, RC Bollineni… - Mass spectrometry …, 2014 - Wiley Online Library
Protein carbonylation, one of the most harmful irreversible oxidative protein modifications, is
considered as a major hallmark of oxidative stress‐related disorders. Protein carbonyl …

SOS, the formidable strategy of bacteria against aggressions

Z Baharoglu, D Mazel - FEMS microbiology reviews, 2014 - academic.oup.com
The presence of an abnormal amount of single-stranded DNA in the bacterial cell constitutes
a genotoxic alarm signal that induces the SOS response, a broad regulatory network found …

Life under extreme energy limitation: a synthesis of laboratory-and field-based investigations

MA Lever, KL Rogers, KG Lloyd… - FEMS microbiology …, 2015 - academic.oup.com
The ability of microorganisms to withstand long periods with extremely low energy input has
gained increasing scientific attention in recent years. Starvation experiments in the …

Oxidative Stress Resistance in Deinococcus radiodurans

D Slade, M Radman - Microbiology and molecular biology reviews, 2011 - Am Soc Microbiol
Deinococcus radiodurans is a robust bacterium best known for its capacity to repair massive
DNA damage efficiently and accurately. It is extremely resistant to many DNA-damaging …

Molecular targets of oxidative stress

SV Avery - Biochemical Journal, 2011 - portlandpress.com
Aerobic life requires organisms to resist the damaging effects of ROS (reactive oxygen
species), particularly during stress. Extensive research has established a detailed picture of …

Conservation and diversity of radiation and oxidative stress resistance mechanisms in Deinococcus species

S Lim, JH Jung, L Blanchard… - FEMS microbiology …, 2019 - academic.oup.com
Deinococcus bacteria are famous for their extreme resistance to ionising radiation and other
DNA damage-and oxidative stress-generating agents. More than a hundred genes have …

Effect of advanced oxidation processes on the micropollutants and the effluent organic matter contained in municipal wastewater previously treated by three different …

S Giannakis, FAG Vives, D Grandjean, A Magnet… - Water Research, 2015 - Elsevier
In this study, wastewater from the output of three different secondary treatment facilities
(Activated Sludge, Moving Bed Bioreactor and Coagulation-Flocculation) present in the …

Proteostasis collapse is a driver of cell aging and death

M Santra, KA Dill, AMR De Graff - Proceedings of the …, 2019 - National Acad Sciences
What molecular processes drive cell aging and death? Here, we model how proteostasis—
ie, the folding, chaperoning, and maintenance of protein function—collapses with age from …

Small-Molecule Antioxidant Proteome-Shields in Deinococcus radiodurans

MJ Daly, EK Gaidamakova, VY Matrosova, JG Kiang… - PloS one, 2010 - journals.plos.org
For Deinococcus radiodurans and other bacteria which are extremely resistant to ionizing
radiation, ultraviolet radiation, and desiccation, a mechanistic link exists between resistance …