Effects of ionizing radiation on biological molecules—mechanisms of damage and emerging methods of detection
Significance: The detrimental effects of ionizing radiation (IR) involve a highly orchestrated
series of events that are amplified by endogenous signaling and culminating in oxidative …
series of events that are amplified by endogenous signaling and culminating in oxidative …
Protein carbonylation as a major hallmark of oxidative damage: update of analytical strategies
Protein carbonylation, one of the most harmful irreversible oxidative protein modifications, is
considered as a major hallmark of oxidative stress‐related disorders. Protein carbonyl …
considered as a major hallmark of oxidative stress‐related disorders. Protein carbonyl …
SOS, the formidable strategy of bacteria against aggressions
The presence of an abnormal amount of single-stranded DNA in the bacterial cell constitutes
a genotoxic alarm signal that induces the SOS response, a broad regulatory network found …
a genotoxic alarm signal that induces the SOS response, a broad regulatory network found …
Life under extreme energy limitation: a synthesis of laboratory-and field-based investigations
The ability of microorganisms to withstand long periods with extremely low energy input has
gained increasing scientific attention in recent years. Starvation experiments in the …
gained increasing scientific attention in recent years. Starvation experiments in the …
Oxidative Stress Resistance in Deinococcus radiodurans
D Slade, M Radman - Microbiology and molecular biology reviews, 2011 - Am Soc Microbiol
Deinococcus radiodurans is a robust bacterium best known for its capacity to repair massive
DNA damage efficiently and accurately. It is extremely resistant to many DNA-damaging …
DNA damage efficiently and accurately. It is extremely resistant to many DNA-damaging …
Molecular targets of oxidative stress
SV Avery - Biochemical Journal, 2011 - portlandpress.com
Aerobic life requires organisms to resist the damaging effects of ROS (reactive oxygen
species), particularly during stress. Extensive research has established a detailed picture of …
species), particularly during stress. Extensive research has established a detailed picture of …
Conservation and diversity of radiation and oxidative stress resistance mechanisms in Deinococcus species
S Lim, JH Jung, L Blanchard… - FEMS microbiology …, 2019 - academic.oup.com
Deinococcus bacteria are famous for their extreme resistance to ionising radiation and other
DNA damage-and oxidative stress-generating agents. More than a hundred genes have …
DNA damage-and oxidative stress-generating agents. More than a hundred genes have …
Effect of advanced oxidation processes on the micropollutants and the effluent organic matter contained in municipal wastewater previously treated by three different …
S Giannakis, FAG Vives, D Grandjean, A Magnet… - Water Research, 2015 - Elsevier
In this study, wastewater from the output of three different secondary treatment facilities
(Activated Sludge, Moving Bed Bioreactor and Coagulation-Flocculation) present in the …
(Activated Sludge, Moving Bed Bioreactor and Coagulation-Flocculation) present in the …
Proteostasis collapse is a driver of cell aging and death
What molecular processes drive cell aging and death? Here, we model how proteostasis—
ie, the folding, chaperoning, and maintenance of protein function—collapses with age from …
ie, the folding, chaperoning, and maintenance of protein function—collapses with age from …
Small-Molecule Antioxidant Proteome-Shields in Deinococcus radiodurans
For Deinococcus radiodurans and other bacteria which are extremely resistant to ionizing
radiation, ultraviolet radiation, and desiccation, a mechanistic link exists between resistance …
radiation, ultraviolet radiation, and desiccation, a mechanistic link exists between resistance …