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Nanoscale covalent organic frameworks: from controlled synthesis to cancer therapy
Covalent organic frameworks (COFs), as a new type of crystalline porous materials, mainly
consist of light-weight elements (H, B, C, N and O) linked by dynamic covalent bonds to form …
consist of light-weight elements (H, B, C, N and O) linked by dynamic covalent bonds to form …
[HTML][HTML] Functionalized liposomes for targeted breast cancer drug delivery
Despite the exceptional progress in breast cancer pathogenesis, prognosis, diagnosis, and
treatment strategies, it remains a prominent cause of female mortality worldwide …
treatment strategies, it remains a prominent cause of female mortality worldwide …
[HTML][HTML] Stimuli-responsive liposomal nanoformulations in cancer therapy: Pre-clinical & clinical approaches
The site-specific delivery of antitumor agents is of importance for providing effective cancer
suppression. Poor bioavailability of anticancer compounds and the presence of biological …
suppression. Poor bioavailability of anticancer compounds and the presence of biological …
Recent preclinical and clinical progress in liposomal doxorubicin
Doxorubicin (DOX) is a potent anti-cancer agent that has garnered great interest in research
due to its high efficacy despite dose-limiting toxicities. Several strategies have been …
due to its high efficacy despite dose-limiting toxicities. Several strategies have been …
[HTML][HTML] Liposomes characterization for market approval as pharmaceutical products: Analytical methods, guidelines and standardized protocols
Liposomes are nano-sized lipid-based vesicles widely studied for their drug delivery
capabilities. Compared to standard carries they exhibit better properties such as improved …
capabilities. Compared to standard carries they exhibit better properties such as improved …
Recent advances in doxorubicin formulation to enhance pharmacokinetics and tumor targeting
J Lee, MK Choi, IS Song - Pharmaceuticals, 2023 - mdpi.com
Doxorubicin (DOX), a widely used drug in cancer chemotherapy, induces cell death via
multiple intracellular interactions, generating reactive oxygen species and DNA-adducted …
multiple intracellular interactions, generating reactive oxygen species and DNA-adducted …
Advances in lipid-based carriers for cancer therapeutics: Liposomes, exosomes and hybrid exosomes
Cancer has recently surpassed heart disease as the leading cause of deaths worldwide for
the age group 45–65 and has been the primary focus for biomedical researchers. Presently …
the age group 45–65 and has been the primary focus for biomedical researchers. Presently …
An updated review of folate-functionalized nanocarriers: A promising ligand in cancer
The uncontrolled release of drugs in conventional drug delivery systems has led to the
introduction of new nanotechnology-based drug delivery systems and the use of targeted …
introduction of new nanotechnology-based drug delivery systems and the use of targeted …
Advances in anti-breast cancer drugs and the application of nano-drug delivery systems in breast cancer therapy
X Fang, J Cao, A Shen - Journal of Drug Delivery Science and Technology, 2020 - Elsevier
Breast cancer is one of the most common malignant tumors among women. Although the
traditional breast cancer therapies are effective, there have numerous shortcomings …
traditional breast cancer therapies are effective, there have numerous shortcomings …
Liposomal doxorubicin as targeted delivery platform: Current trends in surface functionalization
Liposomal delivery systems have significantly enhanced the efficacy and safety of
chemotherapeutic agents compared to free (non-liposomal) formulations. Liposomes are …
chemotherapeutic agents compared to free (non-liposomal) formulations. Liposomes are …