Nanoscale covalent organic frameworks: from controlled synthesis to cancer therapy

X He, Z Jiang, OU Akakuru, J Li, A Wu - Chemical Communications, 2021 - pubs.rsc.org
Covalent organic frameworks (COFs), as a new type of crystalline porous materials, mainly
consist of light-weight elements (H, B, C, N and O) linked by dynamic covalent bonds to form …

[HTML][HTML] Functionalized liposomes for targeted breast cancer drug delivery

J Nel, K Elkhoury, É Velot, A Bianchi, S Acherar… - Bioactive materials, 2023 - Elsevier
Despite the exceptional progress in breast cancer pathogenesis, prognosis, diagnosis, and
treatment strategies, it remains a prominent cause of female mortality worldwide …

[HTML][HTML] Stimuli-responsive liposomal nanoformulations in cancer therapy: Pre-clinical & clinical approaches

M Ashrafizadeh, M Delfi, A Zarrabi, A Bigham… - Journal of controlled …, 2022 - Elsevier
The site-specific delivery of antitumor agents is of importance for providing effective cancer
suppression. Poor bioavailability of anticancer compounds and the presence of biological …

Recent preclinical and clinical progress in liposomal doxorubicin

K Aloss, P Hamar - Pharmaceutics, 2023 - mdpi.com
Doxorubicin (DOX) is a potent anti-cancer agent that has garnered great interest in research
due to its high efficacy despite dose-limiting toxicities. Several strategies have been …

[HTML][HTML] Liposomes characterization for market approval as pharmaceutical products: Analytical methods, guidelines and standardized protocols

S Giordani, V Marassi, A Zattoni, B Roda… - … of pharmaceutical and …, 2023 - Elsevier
Liposomes are nano-sized lipid-based vesicles widely studied for their drug delivery
capabilities. Compared to standard carries they exhibit better properties such as improved …

Recent advances in doxorubicin formulation to enhance pharmacokinetics and tumor targeting

J Lee, MK Choi, IS Song - Pharmaceuticals, 2023 - mdpi.com
Doxorubicin (DOX), a widely used drug in cancer chemotherapy, induces cell death via
multiple intracellular interactions, generating reactive oxygen species and DNA-adducted …

Advances in lipid-based carriers for cancer therapeutics: Liposomes, exosomes and hybrid exosomes

DN Moholkar, R Kandimalla, RC Gupta, F Aqil - Cancer letters, 2023 - Elsevier
Cancer has recently surpassed heart disease as the leading cause of deaths worldwide for
the age group 45–65 and has been the primary focus for biomedical researchers. Presently …

An updated review of folate-functionalized nanocarriers: A promising ligand in cancer

P Ebrahimnejad, AS Taleghani, K Asare-Addo… - Drug discovery today, 2022 - Elsevier
The uncontrolled release of drugs in conventional drug delivery systems has led to the
introduction of new nanotechnology-based drug delivery systems and the use of targeted …

Advances in anti-breast cancer drugs and the application of nano-drug delivery systems in breast cancer therapy

X Fang, J Cao, A Shen - Journal of Drug Delivery Science and Technology, 2020 - Elsevier
Breast cancer is one of the most common malignant tumors among women. Although the
traditional breast cancer therapies are effective, there have numerous shortcomings …

Liposomal doxorubicin as targeted delivery platform: Current trends in surface functionalization

V Makwana, J Karanjia, T Haselhorst… - International Journal of …, 2021 - Elsevier
Liposomal delivery systems have significantly enhanced the efficacy and safety of
chemotherapeutic agents compared to free (non-liposomal) formulations. Liposomes are …