[HTML][HTML] Molecular and cellular mechanisms of propolis and its polyphenolic compounds against cancer

N Oršolić, M Jazvinšćak Jembrek - International journal of molecular …, 2022 - mdpi.com
In recent years, interest in natural products such as alternative sources of pharmaceuticals
for numerous chronic diseases, including tumors, has been renewed. Propolis, a natural …

[HTML][HTML] Quercetin activates the Sestrin2/AMPK/SIRT1 axis to improve amyotrophic lateral sclerosis

T **, Y Zhang, BOA Botchway, M Huang, Q Lu… - Biomedicine & …, 2023 - Elsevier
Amyotrophic lateral sclerosis (ALS) is a chronic neurodegenerative disease with poor
prognosis. The intricacies surrounding its pathophysiology could partly account for the lack …

[HTML][HTML] Polyherbal and multimodal treatments: Kaempferol-and quercetin-rich herbs alleviate symptoms of Alzheimer's disease

C Alexander, A Parsaee, M Vasefi - Biology, 2023 - mdpi.com
Simple Summary Despite the well-documented pathophysiology of Alzheimer's Disease
(AD), treatment options are limited in diversity and efficacy. Thus, the development of new …

Anti-oxidative, anti-inflammatory and anti-apoptotic effects of flavonols: targeting Nrf2, NF-κB and p53 pathways in neurodegeneration

M Jazvinšćak Jembrek, N Oršolić, L Mandić, A Sadžak… - Antioxidants, 2021 - mdpi.com
Neurodegenerative diseases are one of the leading causes of disability and death
worldwide. Intracellular transduction pathways that end in the activation of specific …

[HTML][HTML] Intracellular molecular targets and signaling pathways involved in antioxidative and neuroprotective effects of cannabinoids in neurodegenerative conditions

A Tadijan, I Vlašić, J Vlainić, D Đikić, N Oršolić… - Antioxidants, 2022 - mdpi.com
In the last few decades, endocannabinoids, plant-derived cannabinoids and synthetic
cannabinoids have received growing interest as treatment options in neurodegenerative …

[HTML][HTML] Quercetin: a bioactive compound imparting cardiovascular and neuroprotective benefits: scope for exploring fresh produce, their wastes, and by-products

IUH Bhat, R Bhat - Biology, 2021 - mdpi.com
Simple Summary The present review summarizes the generated hypothesis and critical role
of quercetin in cardiovascular and neuroprotective diseases reported over the last decade …

Dietary plant polyphenols as the potential drugs in neurodegenerative diseases: current evidence, advances, and opportunities

L Yan, MS Guo, Y Zhang, L Yu, JM Wu… - Oxidative medicine …, 2022 - Wiley Online Library
Neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD),
and Huntington's disease (HD), are characterized by the progressive degeneration of …

[HTML][HTML] A comparative analysis of neuroprotective properties of taxifolin and its water-soluble form in ischemia of cerebral cortical cells of the mouse

EG Varlamova, NI Uspalenko, NV Khmil… - International journal of …, 2023 - mdpi.com
Cerebral ischemia, and, as a result, insult, attacks up to 15 million people yearly in the world.
In this connection, the development of effective preventive programs and methods of therapy …

[HTML][HTML] The impact of the phytotherapeutic agent quercetin on expression of genes and activity of signaling pathways

S Ghafouri-Fard, H Shoorei, AK Sasi, M Taheri… - Biomedicine & …, 2021 - Elsevier
Quercetin is a flavonoid existing in different herbs, fruits, seeds, nuts and tea. It has
beneficial effects on human health through mediating antioxidant activities, immune …

The role of copper in tau-related pathology in Alzheimer's disease

K Zubčić, PR Hof, G Šimić… - Frontiers in molecular …, 2020 - frontiersin.org
All tauopathies, including Alzheimer's disease (AD), are characterized by the intracellular
accumulation of abnormal forms of tau protein in neurons and glial cells, which negatively …