Candidiasis is a highly pervasive infection posing major health risks, especially for
immunocompromised populations. Pathogenic Candida species have evolved intrinsic and …

Fungal response to any stress is intricate, specific, and multilayered, though it employs only
a few evolutionarily conserved regulators. This comes with the assumption that one …

Phosphatidylethanolamine (PE) is the second most abundant glycerophospholipid in
eukaryotic cells. The existence of four only partially redundant biochemical pathways that …

Candida albicans is a major fungal pathogen of humans, causing approximately 400,000 life-
threatening systemic infections world-wide each year in severely immunocompromised …

Fluconazole has characteristics that make it widely used in the clinical treatment of C.
albicans infections. However, fluconazole has only a fungistatic activity in C. albicans …

Sterols are the basal components of the membranes of the fungal pathogen Candida
albicans, and these membranes determine the susceptibility of C. albicans cells to a variety …

The balance between reactive oxygen species and reactive nitrogen species production by
the host and stress response by fungi is a key axis of the host-pathogen interaction. This …

Mixed-species biofilm is one of the most frequently recorded clinical problems. Mixed
biofilms develop as a result of interactions between microorganisms of a single or multiple …

While fungi are widely occupying nature, many species are responsible for devastating
mycosis in humans. Such niche diversity explains how quick fungal adaptation is necessary …

Azole drugs are the main therapeutic drugs for invasive fungal infections. However, azole-
resistant strains appear repeatedly in the environment, posing a major threat to human …