There are inherent structural and functional differences in the central nervous systems
(CNS) of females and males. It has been gradually established that these sex-specific …

The contributions of cooperative groups to performing large-cohort clinical trials and long-
term survivorship studies have facilitated advances in treatment, supportive care and …

The diagnosis, treatment, and medical late effects of childhood cancer may alter the
psychosocial trajectory of survivors across their life course. This review of the literature …

Survival rates for most paediatric cancers have improved at a remarkable pace over the past
four decades. In developed countries, cure is now the probable outcome for most children …

Background Serious chronic illness can have a detrimental effect on school attendance,
participation and engagement, leaving affected students at risk of failing to meet their …

This paper presents the evidence for a standard of care for psychosocial assessment in
pediatric cancer. An interdisciplinary group of investigators utilized EBSCO, PubMed …

Survival for childhood cancer has increased dramatically over the last 40 years with 5-year
survival rates now approaching 80%. For many diagnostic groups, rapid increases in …

Background Adult survivors of childhood central nervous system (CNS) malignancies are at
high risk for long-term morbidity and late mortality. However, patterns of late mortality, the …

Difficulties with negotiating and achieving desired social outcomes in life may be
exacerbated by the experience of childhood cancer, including adverse effects from therapies …

Therapy for childhood acute lymphoblastic leukemia (ALL) is associated with 5-year survival
rates of∼ 90% even after largely eliminating cranial radiation. This meta-analysis assesses …