As the most commonly occurring cancer in women worldwide, breast cancer poses a
formidable public health challenge on a global scale. Breast cancer consists of a group of …

Breast cancer is one of the most frequent malignancies among women worldwide. Methods
for screening and diagnosis allow health care professionals to provide personalized …

PURPOSE To update recommendations on appropriate use of breast cancer biomarker
assay results to guide adjuvant endocrine and chemotherapy decisions in early-stage breast …

Breast cancer is treated with a multidisciplinary approach involving surgical oncology,
radiation oncology, and medical oncology. The NCCN Clinical Practice Guidelines in …

Abstract Background The 16th St. Gallen International Breast Cancer Conference 2019 in
Vienna, Austria reviewed substantial new evidence on loco-regional and systemic therapies …

Purpose To update the ASCO clinical practice guideline on adjuvant endocrine therapy
based on emerging data about the optimal duration of aromatase inhibitor (AI) treatment …

Abstract Glutathione peroxidase 4 (GPX4) has been confirmed to inhibit ferroptosis in cancer
cells, however, whether GPX4 serves as an oncogene is not clear. In this study, the …

These NCCN Guidelines Insights highlight the updated recommendations for use of
multigene assays to guide decisions on adjuvant systemic chemotherapy therapy for women …

Abstract Background Kinesin superfamily (KIFs) has a long-reported significant influence on
the initiation, development, and progress of breast cancer. However, the prognostic value of …

Multigene assays for molecular subtypes and biomarkers can aid management of early
invasive breast cancer. Using RNA-sequencing we aimed to develop single-sample …