Galleria mellonella as a Suitable Model of Bacterial Infection: Past, Present and Future

G Ménard, A Rouillon, V Cattoir… - Frontiers in cellular and …, 2021 - frontiersin.org
The increasing interest for Galleria mellonella larvae as an infection model is evidenced by
the number of papers reporting its use, which increases exponentially since the early 2010s …

Galleria mellonella infection models for the study of bacterial diseases and for antimicrobial drug testing

CJY Tsai, JMS Loh, T Proft - Virulence, 2016 - Taylor & Francis
abstract Galleria mellonella (greater wax moth or honeycomb moth) has been introduced as
an alternative model to study microbial infections. G. mellonella larvae can be easily and …

Haemocyte‐mediated immunity in insects: Cells, processes and associated components in the fight against pathogens and parasites

I Eleftherianos, C Heryanto, T Bassal, W Zhang… - …, 2021 - Wiley Online Library
The host defence of insects includes a combination of cellular and humoral responses. The
cellular arm of the insect innate immune system includes mechanisms that are directly …

Thrombosis: tangled up in NETs

K Martinod, DD Wagner - Blood, The Journal of the American …, 2014 - ashpublications.org
The contributions by blood cells to pathological venous thrombosis were only recently
appreciated. Both platelets and neutrophils are now recognized as crucial for thrombus …

Neutrophil extracellular traps: double-edged swords of innate immunity

MJ Kaplan, M Radic - The Journal of Immunology, 2012 - journals.aai.org
Spectacular images of neutrophils ejecting nuclear chromatin and bactericidal proteins, in
response to microbes, were first reported in 2004. As externalized chromatin could entangle …

Entomopathogenic fungi: new insights into host–pathogen interactions

TM Butt, CJ Coates, IM Dubovskiy, NA Ratcliffe - Advances in genetics, 2016 - Elsevier
Although many insects successfully live in dangerous environments exposed to diverse
communities of microbes, they are often exploited and killed by specialist pathogens …

Neutrophil extracellular traps: is immunity the second function of chromatin?

V Brinkmann, A Zychlinsky - Journal of cell biology, 2012 - rupress.org
Neutrophil extracellular traps (NETs) are made of processed chromatin bound to granular
and selected cytoplasmic proteins. NETs are released by white blood cells called …

Immunity of the greater wax moth Galleria mellonella

I Wojda - Insect science, 2017 - Wiley Online Library
Investigation of insect immune mechanisms provides important information concerning
innate immunity, which in many aspects is conserved in animals. This is one of the reasons …

An analysis of the structural and functional similarities of insect hemocytes and mammalian phagocytes

N Browne, M Heelan, K Kavanagh - Virulence, 2013 - Taylor & Francis
The insect immune response demonstrates a number of structural and functional similarities
to the innate immune system of mammals. As a result of these conserved features insects …

At the bench: neutrophil extracellular traps (NETs) highlight novel aspects of innate immune system involvement in autoimmune diseases

PC Grayson, MJ Kaplan - Journal of Leucocyte Biology, 2016 - academic.oup.com
The putative role of neutrophils in host defense against pathogens is a well-recognized
aspect of neutrophil function. The discovery of neutrophil extracellular traps has expanded …