Biomaterials for intervertebral disc regeneration and repair
The intervertebral disc contributes to motion, weight bearing, and flexibility of the spine, but
is susceptible to damage and morphological changes that contribute to pathology with age …
is susceptible to damage and morphological changes that contribute to pathology with age …
Meniscus, articular cartilage and nucleus pulposus: a comparative review of cartilage-like tissues in anatomy, development and function
S Chen, P Fu, H Wu, M Pei - Cell and tissue research, 2017 - Springer
The degradation of cartilage in the human body is impacted by aging, disease, genetic
predisposition and continued insults resulting from daily activity. The burden of cartilage …
predisposition and continued insults resulting from daily activity. The burden of cartilage …
Innovative design of minimal invasive biodegradable poly (glycerol-dodecanoate) nucleus pulposus scaffold with function regeneration
L Wang, K **, N Li, P Xu, H Yuan, H Ramaraju… - Nature …, 2023 - nature.com
Minimally invasive biodegradable implants with regeneration have been a frontier trend in
clinic. Degeneration of nucleus pulposus (NP) is irreversible in most of spine diseases, and …
clinic. Degeneration of nucleus pulposus (NP) is irreversible in most of spine diseases, and …
Materials for the spine: anatomy, problems, and solutions
Disc degeneration affects 12% to 35% of a given population, based on genetics, age,
gender, and other environmental factors, and usually occurs in the lumbar spine due to …
gender, and other environmental factors, and usually occurs in the lumbar spine due to …
Waste to high-value products: The performance and potential of carboxymethylcellulose hydrogels via the circular economy
Hydrogels are a class of materials that have found many applications across society.
Petrochemicals are a dominant, but unsustainable feedstock of crosslinked polymer …
Petrochemicals are a dominant, but unsustainable feedstock of crosslinked polymer …
Degeneration and regeneration of the intervertebral disc: lessons from development
Degeneration of the intervertebral discs, a process characterized by a cascade of cellular,
biochemical, structural and functional changes, is strongly implicated as a cause of low back …
biochemical, structural and functional changes, is strongly implicated as a cause of low back …
Role of biomechanics in intervertebral disc degeneration and regenerative therapies: what needs repairing in the disc and what are promising biomaterials for its …
BACKGROUND CONTEXT: Degeneration and injuries of the intervertebral disc (IVD) result
in large alterations in biomechanical behaviors. Repair strategies using biomaterials can be …
in large alterations in biomechanical behaviors. Repair strategies using biomaterials can be …
Engineering complex anisotropic scaffolds beyond simply uniaxial alignment for tissue engineering
J **ng, N Liu, N Xu, W Chen… - Advanced Functional …, 2022 - Wiley Online Library
Anisotropic microarchitectures arising from an aligned organization of threadlike
extracellular matrix (ECM) components or cells are ubiquitous in the human body, such as …
extracellular matrix (ECM) components or cells are ubiquitous in the human body, such as …
Characterization and properties of carboxymethyl cellulose hydrogels crosslinked by polyethylene glycol
H Kono - Carbohydrate Polymers, 2014 - Elsevier
Novel hydrogels were prepared from carboxymethyl cellulose (CMC) sodium salt by
crosslinking with polyethylene glycol diglycidyl ether (PEGDE). The detailed structures of the …
crosslinking with polyethylene glycol diglycidyl ether (PEGDE). The detailed structures of the …
Recent advancements in polyurethane-based tissue engineering
In tissue engineering, polyurethane-based implants have gained significant traction
because of their high compatibility and inertness. The implants therefore show fewer side …
because of their high compatibility and inertness. The implants therefore show fewer side …