Tackling fungal resistance by biofilm inhibitors
S Wu, Y Wang, N Liu, G Dong… - Journal of Medicinal …, 2017 - ACS Publications
The high incidence and mortality of invasive fungal infections and serious drug resistance
have become a global public health issue. The ability of fungal cells to form biofilms is an …
have become a global public health issue. The ability of fungal cells to form biofilms is an …
Screening repurposing libraries for identification of drugs with novel antifungal activity
G Wall, JL Lopez-Ribot - Antimicrobial Agents and Chemotherapy, 2020 - Am Soc Microbiol
Fungal organisms are ubiquitous in nature, and progress of modern medicine is creating an
expanding number of severely compromised patients susceptible to a variety of …
expanding number of severely compromised patients susceptible to a variety of …
Ultra-fast proteomics with Scanning SWATH
Accurate quantification of the proteome remains challenging for large sample series and
longitudinal experiments. We report a data-independent acquisition method, Scanning …
longitudinal experiments. We report a data-independent acquisition method, Scanning …
Antimicrobial potential of green synthesized CeO2 nanoparticles from Olea europaea leaf extract
This article reports the green fabrication of cerium oxide nanoparticles (CeO2 NPs) using
Olea europaea leaf extract and their applications as effective antimicrobial agents. O …
Olea europaea leaf extract and their applications as effective antimicrobial agents. O …
Prediction of multidimensional drug dose responses based on measurements of drug pairs
A Zimmer, I Katzir, E Dekel… - Proceedings of the …, 2016 - National Acad Sciences
Finding potent multidrug combinations against cancer and infections is a pressing
therapeutic challenge; however, screening all combinations is difficult because the number …
therapeutic challenge; however, screening all combinations is difficult because the number …
Repurposing and optimization of drugs for discovery of novel antifungals
Highlights•There is a dire need for novel antifungal therapies.•Recent clinical trials of directly
repurposed drugs have failed.•The most recently approved antifungals underwent …
repurposed drugs have failed.•The most recently approved antifungals underwent …
Antifungal drug repurposing
JH Kim, LW Cheng, KL Chan, CC Tam, N Mahoney… - Antibiotics, 2020 - mdpi.com
Control of fungal pathogens is increasingly problematic due to the limited number of
effective drugs available for antifungal therapy. Conventional antifungal drugs could also …
effective drugs available for antifungal therapy. Conventional antifungal drugs could also …
Drug repurposing in medical mycology: Identification of compounds as potential antifungals to overcome the emergence of multidrug-resistant fungi
L Peyclit, H Yousfi, JM Rolain, F Bittar - Pharmaceuticals, 2021 - mdpi.com
Immunodepression, whether due to HIV infection or organ transplantation, has increased
human vulnerability to fungal infections. These conditions have created an optimal …
human vulnerability to fungal infections. These conditions have created an optimal …
Eucalyptol/β-cyclodextrin inclusion complex loaded gellan/PVA nanofibers as antifungal drug delivery system
Fungal infections pose a serious threat to humankind due to the toxicity of conventional
antifungal therapy and continuous emerging incidence of multidrug resistance. Essential oils …
antifungal therapy and continuous emerging incidence of multidrug resistance. Essential oils …
Combination therapy to treat fungal biofilm-based infections
J Tits, BPA Cammue, K Thevissen - International Journal of Molecular …, 2020 - mdpi.com
An increasing number of people is affected by fungal biofilm-based infections, which are
resistant to the majority of currently-used antifungal drugs. Such infections are often caused …
resistant to the majority of currently-used antifungal drugs. Such infections are often caused …