Among many, the oral route of delivery is considered to be the most favorable route with the
highest patient compliance. The main issue with oral delivery is the environmental …

The anti-metabolite drug gemcitabine is widely used for the treatment of a variety of cancers.
At present, gemcitabine is administered as a hydrochloride salt that is delivered by slow …

This study aims to encapsulate gemcitabine (GEM) using a phospholipid complex (PLC) in
lipid nanoparticles (NPs) to achieve several desirable outcomes, including high drug …

Conclusively, the in vivo toxicity revealed safety and biocompatibility, and the developed
system could be used as an effective delivery for various therapeutic agents. Similar reports …

Triple-negative breast cancer (TNBC) belongs to the category of the most destructive forms
of breast cancer. Being a highly potent chemotherapeutic agent, paclitaxel (PTX) is …

Dihydromyricetin (DMY), a flavanonol compound found as the most abundant and bioactive
constituent in Ampelopsis grossedentata (Hand-Mazz) WT Wang, possesses numerous …

This study investigated the cytotoxic effects of gemcitabine-loaded solid lipid nanoparticle
(Gem-SLN) on the patient-derived primary pancreatic cancer cell lines (PPCL-46) and …

Evidences have shown that phytosome assemblies are novel drug delivery system.
However, studies of phytosomes in food applications are scarce. The characteristics of milk …

The current study was aimed to prepare a molecular complex of erlotinib (ERL) with
phospholipid (PC) for enhancement of solubility and thus bioavailability, therapeutic efficacy …

Phospholipid complexes of alkyl gallates (A-GAs) including ethyl gallate (EG), propyl gallate
(PG), and butyl gallate (BG) were successfully prepared by the thin film dispersion method …